Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23643807 | 0.96 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1MAPK1HPGDMAPT | |
| SCHEMBL23643545 | 0.86 | ALDH1A1 (0.72) | ALDH1A1L3MBTL1MAPK1SMN1; SMN2LMNA | |
| SCHEMBL18954295 | 0.84 | ALDH1A1 (0.75) | ALDH1A1L3MBTL1MAPK1SMN1; SMN2RAB9A | |
| SCHEMBL23643789 | 0.80 | L3MBTL1 (0.50) | ALDH1A1L3MBTL1MAPK1HPGDMAPT | |
| SCHEMBL22970829 | 0.79 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1MAPK1HPGDMAPT | |
| SCHEMBL20712042 | 0.79 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1MAPK1HPGDMAPT | |
| Hydrochloric Acid SCHEMBL11681830 | 0.78 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1MAPK1HPGDMAPT | |
| SCHEMBL8009812 | 0.78 | NPC1 (0.53) | ALDH1A1L3MBTL1MAPK1HPGDMAPT | |
| SCHEMBL8644740 | 0.77 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1MAPK1HPGDMAPT | |
| SCHEMBL6973123 | 0.77 | LTA4H (0.45) | ALDH1A1L3MBTL1MAPK1HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210214374-A1 | COMPOUNDS AND COMPOSITIONS FOR OCULAR DELIVERY | Graybug Vision, Inc. (US) | 2021-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210214374-A1 | COMPOUNDS AND COMPOSITIONS FOR OCULAR DELIVERY | KDR, RB1, PDE6C | ALDH1A1 2125/4885L3MBTL1 4766/4885MAPK1 785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.