Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20520865 | 0.89 | PDE4B (0.47) | PDE4BOPRK1 | |
| SCHEMBL25335713 | 0.81 | LMNA (0.30) | — | |
| SCHEMBL20520654 | 0.78 | PDE4B (0.46) | PDE4B | |
| SCHEMBL29705143 | 0.78 | PDE4B (0.46) | PDE4B | |
| SCHEMBL20520759 | 0.77 | GSK3B (0.31) | CNR2 | |
| SCHEMBL29705203 | 0.77 | GSK3B (0.31) | CNR2 | |
| SCHEMBL28735837 | 0.76 | LMNA (0.33) | BACE1 | |
| SCHEMBL27696252 | 0.73 | HSD17B10 (0.36) | OPRK1 | |
| SCHEMBL20240708 | 0.72 | LMNA (0.34) | — | |
| SCHEMBL23646765 | 0.70 | LMNA (0.44) | PDE4BOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3601282-B1 | NOVEL PYRIDO[2,3-B]INDOLE COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF BACTERIAL INFECTION | HOFFMANN LA ROCHE (CH) | 2021-07-21 | — | — | EP | disclosed |