Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 10/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20520654 | 1.00 | PDE4B (0.46) | PDE4BHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL20520865 | 0.89 | PDE4B (0.47) | PDE4BHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL29705146 | 0.83 | KDM4E (0.35) | PDE4BHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL20521183 | 0.83 | KDM4E (0.35) | PDE4BHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL20521561 | 0.80 | KDM4E (0.35) | PDE4BHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL29705123 | 0.80 | KDM4E (0.35) | PDE4BHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL20521542 | 0.79 | PDE4B (0.36) | PDE4BPOLB | |
| SCHEMBL23644684 | 0.78 | PDE4B (0.35) | PDE4B | |
| SCHEMBL20521059 | 0.77 | KDM4E (0.40) | PDE4BHSD17B10KDM4EALDH1A1HPGD | |
| SCHEMBL29705131 | 0.77 | KDM4E (0.40) | PDE4BHSD17B10KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110475777-B | Novel pyrido [2,3-b ] indole compounds for the treatment and prevention of bacterial infections | 豪夫迈·罗氏有限公司 | 2022-04-15 | — | — | CN | disclosed |