SCHEMBL23645008

SCHEMBL23645008

CCc1oc2c(=O)c3ccccc3n(C(C)C)c2c1-c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
KDM4E B2RXH2 4/20 0.38
POLB P06746 2/20 0.38
CYP2C19 P33261 2/20 0.38
KMT2A Q03164 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
MEN1 O00255 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
RCE1 Q9Y256 1/20 0.38
CDC25A P30304 1/20 0.36
CDC25C P30307 1/20 0.36
PRKD3 O94806 1/20 0.36
PRKCG P05129 1/20 0.36
PRKCB P05771 1/20 0.36
PRKCA P17252 1/20 0.36
PRKCH P24723 1/20 0.36
PRKCI P41743 1/20 0.36
PRKCE Q02156 1/20 0.36
PRKCQ Q04759 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20034024 0.84 KMT2A (0.40) ALDH1A1KDM4EPOLBCYP2C19KMT2A
SCHEMBL26877343 0.84 KDM4E (0.43) ALDH1A1KDM4EPOLBCYP2C19KMT2A
SCHEMBL23645526 0.77 ALDH1A1 (0.48) ALDH1A1KDM4EPOLBTDP1RCE1
SCHEMBL22927262 0.72 POLB (0.40) ALDH1A1KDM4EPOLBCYP2C19KMT2A
SCHEMBL18610650 0.71 POLB (0.44) ALDH1A1KDM4EPOLBCYP2C19KMT2A
SCHEMBL18722227 0.71 POLB (0.41) ALDH1A1POLBCYP2C19KMT2ATDP1
SCHEMBL20033984 0.70 KDM4E (0.49) ALDH1A1KDM4EPOLBCYP2C19KMT2A
SCHEMBL20034031 0.70 ALDH1A1 (0.41) ALDH1A1KDM4EPOLBCYP2C19KMT2A
SCHEMBL13545619 0.68 MAPT (0.54) ALDH1A1KDM4EPOLBCYP2C19KMT2A
SCHEMBL14160799 0.68 ALDH1A1 (0.53) ALDH1A1KDM4EPOLBCYP2C19KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210217973-A1 Tetradentate Cyclometalated Platinum Complexes Containing 9,10-Dihydroacridine And Its Analogues UNIV ARIZONA STATE (US) 2021-07-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210217973-A1 Tetradentate Cyclometalated Platinum Complexes Containing 9,10-Dihydroacridine And Its Analogues DPYD, DCTD, TYMP ALDH1A1 1020/4885KDM4E 4749/4885POLB 179/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.