Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | CDC25A | P30304 | 1/20 | 0.39 |
| ▸ | CDC25C | P30307 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | PRKCG | P05129 | 1/20 | 0.39 |
| ▸ | PRKCB | P05771 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | PRKCH | P24723 | 1/20 | 0.39 |
| ▸ | PRKCI | P41743 | 1/20 | 0.39 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23645526 | 0.83 | ALDH1A1 (0.48) | ALDH1A1TDP1KDM4ENR1I2EGFR | |
| SCHEMBL20034014 | 0.82 | SYK (0.43) | ALDH1A1TDP1KDM4ENR1I2EGFR | |
| SCHEMBL18722102 | 0.81 | TDP1 (0.40) | ALDH1A1TDP1NR1I2EGFRADRA2A | |
| SCHEMBL20034024 | 0.75 | KMT2A (0.40) | ALDH1A1TDP1KDM4ENR1I2EGFR | |
| SCHEMBL14160799 | 0.74 | ALDH1A1 (0.53) | ALDH1A1TDP1KDM4ECDC25ACDC25C | |
| SCHEMBL26877343 | 0.73 | KDM4E (0.43) | ALDH1A1TDP1KDM4ENR1I2EGFR | |
| SCHEMBL23072093 | 0.72 | POLB (0.41) | ALDH1A1TDP1CDC25ACDC25CPRKD3 | |
| SCHEMBL23645008 | 0.70 | ALDH1A1 (0.41) | ALDH1A1TDP1KDM4ENR1I2EGFR | |
| SCHEMBL16640327 | 0.70 | MAPT (0.43) | ALDH1A1TDP1CDC25ACDC25CPRKD3 | |
| SCHEMBL23072143 | 0.69 | ALDH1A1 (0.43) | ALDH1A1TDP1PRKD3PRKCGPRKCB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9941479-B2 | Tetradentate cyclometalated platinum complexes containing 9,10-dihydroacridine and its analogues | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2018-04-10 | — | — | US | disclosed |