Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6496067 | 0.80 | KCNJ5 (0.66) | MAPTTSHRLMNASMN1; SMN2HPGD | |
| SCHEMBL8639229 | 0.80 | MAPT (0.71) | MAPTTSHRLMNASMN1; SMN2ATM | |
| SCHEMBL10340210 | 0.80 | MAPT (0.71) | MAPTTSHRLMNASMN1; SMN2GAA | |
| SCHEMBL10340271 | 0.80 | KDM4E (0.77) | MAPTTSHRLMNASMN1; SMN2HPGD | |
| SCHEMBL22340613 | 0.78 | RXFP1 (0.60) | MAPTTSHRLMNASMN1; SMN2HPGD | |
| SCHEMBL5142574 | 0.77 | POLB (0.76) | SMN1; SMN2HPGDGAAMEN1KMT2A | |
| SCHEMBL8049389 | 0.77 | MEN1 (0.76) | MAPTTSHRSMN1; SMN2GAAMEN1 | |
| SCHEMBL11620710 | 0.77 | POLB (0.73) | LMNASMN1; SMN2HPGDATMGAA | |
| SCHEMBL31393812 | 0.77 | MEN1 (0.76) | MAPTTSHRSMN1; SMN2GAAMEN1 | |
| SCHEMBL4778269 | 0.76 | POLB (0.65) | LMNASMN1; SMN2HPGDGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | claimed |