Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 4/20 | 0.62 |
| ▸ | GFER | P55789 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.54 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10340271 | 0.89 | KDM4E (0.77) | MAPTMAPK8TSHRKDM4EALDH1A1 | |
| SCHEMBL10340210 | 0.89 | MAPT (0.71) | MAPTMAPK8TSHRKDM4EALDH1A1 | |
| SCHEMBL8639959 | 0.86 | KDM4E (0.60) | MAPTMAPK8TSHRKDM4EALDH1A1 | |
| SCHEMBL10340244 | 0.84 | MAPK8 (0.62) | MAPTMAPK8TSHRKDM4EALDH1A1 | |
| SCHEMBL31239080 | 0.82 | NPC1 (0.70) | MAPTTSHRKDM4EALDH1A1HSD17B10 | |
| SCHEMBL8637152 | 0.81 | GAA (0.64) | KDM4EGAAGFERLMNASMN1; SMN2 | |
| SCHEMBL8638027 | 0.80 | MEN1 (0.67) | MAPTKDM4EALDH1A1GAAGFER | |
| SCHEMBL22340657 | 0.80 | TSHR (0.75) | MAPTTSHRKDM4EHSD17B10GAA | |
| SCHEMBL2364548 | 0.80 | MAPT (0.69) | MAPTTSHRKDM4EALDH1A1HSD17B10 | |
| SCHEMBL8636686 | 0.78 | MAPK8 (0.67) | MAPK8KDM4EALDH1A1GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0855387-A1 | 2-ACYLAMINOBENZAMIDE DERIVATIVES AND PREVENTIVE AND REMEDY FOR DISEASES CAUSED BY THE SUPERMULTIPLICATION OF VASCULAR INTIMAL CELLS | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1998-07-29 | — | — | EP | disclosed |