Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM4 | O15151 | 4/20 | 0.68 |
| ▸ | TP53 | P04637 | 4/20 | 0.68 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.55 |
| ▸ | CETP | P11597 | 9/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29519193 | 0.83 | SMN1; SMN2 (0.54) | MDM4TP53NPC1RAB9AHPGD | |
| SCHEMBL1226530 | 0.83 | SMN1; SMN2 (0.54) | MDM4TP53NPC1RAB9AHPGD | |
| SCHEMBL31126466 | 0.82 | TP53 (0.62) | MDM4TP53MDM2CETPMAPT | |
| SCHEMBL8873467 | 0.82 | TP53 (0.62) | MDM4TP53MDM2CETPMAPT | |
| SCHEMBL333488 | 0.81 | MDM4 (1.00) | MDM4TP53MDM2MAPTNPC1 | |
| SCHEMBL1534004 | 0.80 | MDM4 (0.66) | MDM4TP53MDM2CETPNPC1 | |
| SCHEMBL5595124 | 0.79 | TP53 (0.65) | MDM4TP53MAPTNPC1RAB9A | |
| SCHEMBL6002243 | 0.79 | MDM4 (0.96) | MDM4TP53MDM2MAPTNPC1 | |
| SCHEMBL12841231 | 0.77 | MDM4 (1.00) | MDM4TP53MDM2CETPMAPT | |
| SCHEMBL7159123 | 0.77 | KDM4E (0.69) | MDM4TP53MAPTHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8003587-B2 | Semiconductor process residue removal composition and process | EKC TECHNOLOGY, INC. (US) | 2011-08-23 | — | — | US | disclosed |
| EP-2229391-A1 | PYRIDO[2,3-B]PYRAZINE-8-SUBSTITUTED COMPOUNDS AND THEIR USE | Cancer Research Technology Limited (GB) | 2010-09-22 | — | — | EP | disclosed |
| US-20090203566-A1 | Semi Conductor Process Residue Removal Composition and Process | EKC TECHNOLOGY, INC. | 2009-08-13 | — | — | US | disclosed |
| WO-2009077766-A1 | PYRIDO[2,3-B]PYRAZINE-8-SUBSTITUTED COMPOUNDS AND THEIR USE | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2009-06-25 | — | — | WO | disclosed |