SCHEMBL1226530

SCHEMBL1226530

O=C(O)Nc1ccccc1NC(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.54
ALDH1A1 P00352 2/20 0.54
RECQL P46063 1/20 0.54
NPC1 O15118 2/20 0.52
RAB9A P51151 2/20 0.52
HPGD P15428 3/20 0.50
POLB P06746 2/20 0.50
TP53 P04637 3/20 0.48
MAPK1 P28482 3/20 0.48
LMNA P02545 1/20 0.48
HTT P42858 1/20 0.48
EPHX1 P07099 1/20 0.48
TSHR P16473 1/20 0.48
EPHX2 P34913 1/20 0.48
CDK9 P50750 1/20 0.48
CLK4 Q9HAZ1 1/20 0.48
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
KDM4E B2RXH2 1/20 0.46
GAA P10253 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29519193 1.00 SMN1; SMN2 (0.54) SMN1; SMN2ALDH1A1RECQLNPC1RAB9A
SCHEMBL665339 0.85 RAB9A (0.75) ALDH1A1NPC1RAB9AHPGDPOLB
SCHEMBL612151 0.85 NPC1 (0.61) ALDH1A1NPC1RAB9AHPGDTP53
SCHEMBL10828925 0.85 RAB9A (0.45) SMN1; SMN2ALDH1A1RECQLNPC1RAB9A
Methacrylic Acid SCHEMBL21905373 0.84 ALDH1A1 (0.48) SMN1; SMN2ALDH1A1RECQLNPC1RAB9A
SCHEMBL2097652 0.83 CYP1A2 (0.62) SMN1; SMN2ALDH1A1NPC1RAB9AHPGD
SCHEMBL13004744 0.83 RAB9A (0.43) SMN1; SMN2ALDH1A1RECQLNPC1RAB9A
SCHEMBL3826923 0.83 RAB9A (0.43) SMN1; SMN2ALDH1A1RECQLNPC1RAB9A
SCHEMBL2364554 0.83 MDM4 (0.68) SMN1; SMN2ALDH1A1RECQLNPC1RAB9A
SCHEMBL653241 0.83 HDAC3 (0.68) ALDH1A1NPC1RAB9AMAPK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011012659-A2 DIETHYL 4-(4-FLUOROBENZYLAMINO)-1,2-PHENYLENEDICARBAMATE, AND SALTS THEREOF MEDICHEM S.A. (ES) 2011-02-03 WO claimed
EP-3651253-B1 POLYMER SOLID ELECTROLYTE, METHOD OF MAKING THE SAME, AND ELECTROCHEMICAL CELL FACTORIAL INC (US) 2024-02-14 EP disclosed
US-20230344001-A1 POLYMER SOLID ELECTROLYTES, METHODS OF MAKING, AND ELECTROCHEMICAL CELLS COMPRISING THE SAME FACTORIAL INC. 2023-10-26 US disclosed
US-11735770-B2 Polymer solid electrolytes, methods of making, and electrochemical cells comprising the same FACTORIAL INC. (US) 2023-08-22 US disclosed
CN-111154093-B Polymer solid electrolyte, method for producing the same, and electrochemical cell 飞翼新能源公司 2023-05-05 CN disclosed
US-11335950-B2 Polymer solid electrolytes FACTORIAL INC. (US) 2022-05-17 US disclosed
CN-114269794-A Catalyst components for the polymerization of olefins 巴塞尔聚烯烃意大利有限公司 2022-04-01 CN disclosed
US-20210151794-A9 POLYMER SOLID ELECTROLYTES LIONANO SE INC. (US) 2021-05-20 US disclosed
US-20210151795-A9 POLYMER SOLID ELECTROLYTES, METHODS OF MAKING, AND ELECTROCHEMICAL CELLS COMPRISING THE SAME LIONANO SE INC. (US) 2021-05-20 US disclosed
CN-111154093-A Polymer solid electrolyte, method for preparing same, and electrochemical cell 林奈(SE)公司 2020-05-15 CN disclosed
EP-2651885-A1 ANTI-VIRAL COMPOUNDS Abbvie Inc. (US) 2013-10-23 EP disclosed
WO-2013011518-A1 PROCESS FOR THE PREPARATION OF RETIGABINE OF THE FORMULA I AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF ARCH PHARMALABS LIMITED (IN) 2013-01-24 WO disclosed
WO-2012083170-A1 ANTI-VIRAL COMPOUNDS ABBOTT LABORATORIES (US) 2012-06-21 WO disclosed
WO-2011012659-A2 DIETHYL 4-(4-FLUOROBENZYLAMINO)-1,2-PHENYLENEDICARBAMATE, AND SALTS THEREOF MEDICHEM S.A. (ES) 2011-02-03 WO disclosed
WO-2008153286-A2 AROMATIC DIAMINES WITH A PHOTOREACTIVE AROMATIC SIDE GROUP, POLYAMIC ACID PHOTO-ALIGNMENT LAYERS WITH THEM AND METHOD FOR PREPARING LIQUID CRYSTAL CELLS KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2008-12-18 WO disclosed
EP-0555628-B1 Process for preparing isocyanates NIPPON CATALYTIC CHEM IND (JP) 1996-05-29 EP disclosed
US-5326903-A Thermal decomposition of carbamate NIPPON SHOKUBAI CO., LTD. (JP) 1994-07-05 US disclosed
EP-0555628-A2 Process for preparing isocyanates NIPPON SHOKUBAI CO., LTD. (JP) 1993-08-18 EP disclosed
EP-0101807-B1 TETRAMETHACRYLIC OR TETRAACRYLIC ACID COMPOUNDS AND THEIR USE Blendax-Werke R. Schneider GmbH & Co. (DE) 1987-03-25 EP disclosed
US-3997553-A 2-Benzimidazolecarbamic acid esters by the cyanamide process E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-12-14 US disclosed