SCHEMBL333488

SCHEMBL333488

O=C(Nc1ccccc1S)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MDM4 O15151 5/20 1.00
TP53 P04637 5/20 1.00
MDM2 Q00987 3/20 0.74
HDAC3 O15379 2/20 0.61
HDAC1 Q13547 2/20 0.61
HDAC2 Q92769 2/20 0.61
MAPK1 P28482 1/20 0.61
POLB P06746 1/20 0.61
HPGD P15428 1/20 0.61
KMT2A Q03164 4/20 0.59
MEN1 O00255 3/20 0.59
MAPT P10636 2/20 0.59
TDP1 Q9NUW8 2/20 0.59
PKM P14618 2/20 0.59
GRIK1 P39086 1/20 0.59
NPC1 O15118 2/20 0.58
RAB9A P51151 2/20 0.58
CYP1A2 P05177 1/20 0.58
CYP3A4 P08684 1/20 0.58
CYP2D6 P10635 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6002243 0.98 MDM4 (0.96) MDM4TP53MDM2HDAC3HDAC1
SCHEMBL1520421 0.85 MEN1 (0.77) MDM4TP53MDM2HDAC1POLB
SCHEMBL1110180 0.85 MDM4 (0.73) MDM4TP53HDAC3HDAC1HDAC2
SCHEMBL29604506 0.84 TP53 (0.72) MDM4TP53MDM2HDAC3HDAC1
SCHEMBL24389088 0.84 TP53 (0.72) MDM4TP53MDM2HDAC3HDAC1
SCHEMBL7296052 0.83 MDM4 (0.70) MDM4TP53MDM2MAPK1POLB
SCHEMBL2364554 0.81 MDM4 (0.68) MDM4TP53MDM2POLBHPGD
SCHEMBL13212312 0.80 NPC1 (0.71) MDM4TP53MDM2POLBKMT2A
SCHEMBL29020526 0.80 MDM4 (0.67) MDM4TP53HDAC3HDAC1HDAC2
SCHEMBL7154697 0.79 MDM4 (0.66) MDM4TP53MDM2POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 237 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0672719-B1 Rubber compounds containing vulcanized scrap rubber and methods of manufacturing such rubber compounds MAZDA MOTOR (JP) 1999-12-29 EP claimed
US-5556888-A RUBBER WITH POWDERED VULCANIZED SCRAP RUBBER WITH SURFACE TREATED WITH SWELLING AND VULCANIZATION MAZDA MOTOR CORPORATION (JP) 1996-09-17 US claimed
US-5252652-A Core of rubber, unsaturated carboxylic acid metal salt, organic sulfur compound and organic peroxide BRIDGESTONE CORPORATION (JP) 1993-10-12 US claimed
JP-1278543-A None JP disclosed
JP-9003120-A None JP disclosed
JP-55135147-A None JP disclosed
US-12623121-B1 Golf ball TAYLOR MADE GOLF COMPANY, INC. (US) 2026-05-12 US disclosed
US-12420146-B2 Golf ball TAYLOR MADE GOLF COMPANY, INC. (US) 2025-09-23 US disclosed
US-20250288872-A1 MULTI-COLOR URETHANE GOLF BALL TAYLOR MADE GOLF COMPANY, INC. (US) 2025-09-18 US disclosed
US-20250242208-A1 GOLF BALL WITH SOFTER FEEL AND HIGHER IRON SPIN TAYLOR MADE GOLF COMPANY, INC. (US) 2025-07-31 US disclosed
US-20250195958-A1 GOLF BALL TAYLOR MADE GOLF COMPANY, INC. (US) 2025-06-19 US disclosed
US-5252652-A Core of rubber, unsaturated carboxylic acid metal salt, organic sulfur compound and organic peroxide BRIDGESTONE CORPORATION (JP) 1993-10-12 US disclosed
EP-0280241-B1 PLATEN ROLLER CANON KABUSHIKI KAISHA (JP) 1992-07-22 EP disclosed
US-5008138-A With cylindrical rubber synthesized by vulcanizing a blend polymer; impact strength, shockproof CANON KABUSHIKI KAISHA (JP) 1991-04-16 US disclosed
US-4981381-A TYPEWRITER CANON KABUSHIKI KAISHA (JP) 1991-01-01 US disclosed
JP-H01278543-A RUBBER COMPOSITION SANSHIN CHEM IND CO LTD 1989-11-08 JP disclosed
EP-0280241-A2 Platen roller CANON KABUSHIKI KAISHA (JP) 1988-08-31 EP disclosed
US-4722977-A AROMATIC MERCAPTANS, DISULFIDES, IRON SALTS AND COMPLEXES AS BOOSTERS BAYER AKTIENGESELLSCHAFT (DE) 1988-02-02 US disclosed
EP-0157079-A2 Process and product for decreasing the viscosity of elastomers BAYER AG (DE) 1985-10-09 EP disclosed
JP-S55135147-A PREVENTION OF SCORCHING OF HALOGEN-CONTAINING POLYMER RUBBER SANSHIN KAGAKU KOGYO KK 1980-10-21 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12623121-B1 Golf ball ADAMTS4, ADAMTS13, MACF1 MDM4 839/4885TP53 1624/4885MDM2 3347/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.