Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 6/20 | 0.61 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23645587 | 0.81 | DHODH (0.62) | DHODHPARP1 | |
| SCHEMBL23644566 | 0.81 | DHODH (0.50) | DHODH | |
| SCHEMBL24060234 | 0.79 | DHODH (0.52) | DHODHPARP1CD274PDCD1 | |
| SCHEMBL21905230 | 0.76 | DHODH (1.00) | DHODH | |
| SCHEMBL23645726 | 0.75 | DHODH (0.42) | DHODHPTGER4FFAR1FFAR4 | |
| SCHEMBL15973487 | 0.74 | DHODH (0.59) | DHODHPARP1 | |
| SCHEMBL25939558 | 0.74 | DHODH (0.59) | DHODHFFAR1 | |
| SCHEMBL23645729 | 0.73 | DHODH (0.56) | DHODH | |
| Trifluoroacetic Acid SCHEMBL26136771 | 0.72 | DHODH (0.92) | DHODH | |
| SCHEMBL24060387 | 0.70 | DHODH (0.50) | DHODHPTGER4FFAR1FFAR4PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3615027-B1 | METHODS OF USE FOR TRISUBSTITUTED BENZOTRIAZOLE DERIVATIVES AS DIHYDROOROTATE OXYGENASE INHIBITORS | AURIGENE DISCOVERY TECH LTD (IN) | 2021-07-14 | — | — | EP | disclosed |