Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.52 |
| ▸ | LSS | P48449 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13544149 | 0.91 | HRH3 (0.71) | HRH3ALDH1A1KDM4EPOLBKCNH2 | |
| SCHEMBL23644642 | 0.82 | HRH3 (0.62) | HRH3ALDH1A1KDM4EPOLBKCNH2 | |
| SCHEMBL23645706 | 0.80 | HRH3 (0.63) | HRH3ALDH1A1KDM4EKCNH2PARP1 | |
| SCHEMBL23645597 | 0.79 | HRH3 (0.58) | HRH3ALDH1A1KDM4EPOLBKCNH2 | |
| SCHEMBL24522256 | 0.79 | HRH3 (0.71) | HRH3ALDH1A1KDM4EPARP1 | |
| SCHEMBL16480464 | 0.79 | ALDH1A1 (0.66) | HRH3ALDH1A1KDM4EPARP1 | |
| SCHEMBL1639518 | 0.78 | HRH3 (0.72) | HRH3KCNH2 | |
| SCHEMBL4610176 | 0.78 | ALDH1A1 (0.64) | HRH3ALDH1A1KDM4EPOLBPARP1 | |
| SCHEMBL3562026 | 0.78 | ALDH1A1 (0.90) | HRH3ALDH1A1KDM4EPOLBPARP1 | |
| SCHEMBL4770791 | 0.78 | ALDH1A1 (0.64) | HRH3ALDH1A1KDM4EPOLBPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210213005-A1 | PYRROLIDINE GLYCOSIDASE INHIBITORS | ASCENEURON SA (CH) | 2021-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210213005-A1 | PYRROLIDINE GLYCOSIDASE INHIBITORS | PREP, GAA, DNPEP | HRH3 2645/4885ALDH1A1 1170/4885KDM4E 1934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.