Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 13/20 | 0.44 |
| ▸ | SPHK2 | Q9NRA0 | 13/20 | 0.44 |
| ▸ | NOS1 | P29475 | 4/20 | 0.33 |
| ▸ | NOS2 | P35228 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23645821 | 0.95 | SPHK1 (0.38) | SPHK1SPHK2 | |
| SCHEMBL23645805 | 0.79 | CYP19A1 (0.34) | SPHK1SPHK2NOS1NOS2 | |
| SCHEMBL23645846 | 0.72 | SPHK1 (0.38) | SPHK1SPHK2 | |
| SCHEMBL23645803 | 0.71 | ALDH1A1 (0.30) | — | |
| SCHEMBL23645850 | 0.70 | ALDH1A1 (0.32) | SPHK1SPHK2 | |
| SCHEMBL673896 | 0.69 | ALDH1A1 (0.39) | SPHK1 | |
| SCHEMBL23645606 | 0.67 | EPHX1 (0.38) | SPHK1SPHK2 | |
| SCHEMBL23533458 | 0.67 | ALOX5 (0.45) | — | |
| SCHEMBL21746023 | 0.65 | — | — | |
| SCHEMBL2877408 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2625190-B1 | DERIVATIVES OF STEROID BENZYLAMINES, HAVING AN ANTIPARASITIC, ANTIBACTERIAL, ANTIMYCOTIC AND/OR ANTIVIRAL ACTION | UNIV JUSTUS LIEBIG GIESSEN (DE) | 2021-07-14 | — | — | EP | disclosed |