SCHEMBL23645841

SCHEMBL23645841

Oc1ccc(Br)cc1CNI

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.56
PKM P14618 2/20 0.56
CYP1A2 P05177 2/20 0.56
CYP2C9 P11712 2/20 0.56
CYP3A4 P08684 1/20 0.56
HIF1A Q16665 1/20 0.56
CA12 O43570 2/20 0.50
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA9 Q16790 2/20 0.50
TSHR P16473 2/20 0.46
GFER P55789 1/20 0.46
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
APAF1 O14727 1/20 0.46
ALOX15 P16050 2/20 0.45
HPGD P15428 4/20 0.44
HTT P42858 3/20 0.44
MAPT P10636 3/20 0.44
MAPK1 P28482 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8821719 0.80 CA12 (0.60) ALDH1A1PKMCYP1A2CYP2C9CYP3A4
SCHEMBL2889487 0.80 ALDH1A1 (0.56) ALDH1A1PKMCYP1A2CYP2C9CYP3A4
SCHEMBL15071461 0.77 ALDH1A1 (0.53) ALDH1A1PKMCYP1A2CYP2C9CYP3A4
SCHEMBL14496519 0.77 ALOX15 (0.50) ALDH1A1PKMCYP1A2CYP2C9CYP3A4
SCHEMBL68224 0.76 ALOX15 (0.54) ALDH1A1PKMCYP1A2CYP2C9CYP3A4
SCHEMBL13219436 0.76 MEN1 (0.61) ALDH1A1PKMCYP2C9CYP3A4HIF1A
Hydrochloric Acid SCHEMBL7667121 0.76 ALDH1A1 (0.51) ALDH1A1PKMCYP1A2CYP2C9CYP3A4
SCHEMBL11593064 0.76 MEN1 (0.52) ALDH1A1PKMCYP1A2CYP2C9CYP3A4
SCHEMBL12502495 0.76 ALDH1A1 (0.51) ALDH1A1PKMCYP1A2CYP2C9CYP3A4
SCHEMBL149179 0.74 CA12 (0.64) ALDH1A1PKMCYP1A2CYP2C9CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2625190-B1 DERIVATIVES OF STEROID BENZYLAMINES, HAVING AN ANTIPARASITIC, ANTIBACTERIAL, ANTIMYCOTIC AND/OR ANTIVIRAL ACTION UNIV JUSTUS LIEBIG GIESSEN (DE) 2021-07-14 EP disclosed