SCHEMBL34240

SCHEMBL34240

Oc1ccc2cc[nH]c2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 1.00
USP2 O75604 1/20 0.68
GAA P10253 1/20 0.68
ALOX15 P16050 1/20 0.68
RAD51 Q06609 1/20 0.68
NPSR1 Q6W5P4 1/20 0.68
AHR P35869 4/20 0.56
CMA1 P23946 1/20 0.56
ENPP2 Q13822 2/20 0.55
KDM4E B2RXH2 1/20 0.53
ALDH1A1 P00352 1/20 0.53
HPGD P15428 1/20 0.53
HSD17B10 Q99714 1/20 0.53
BACE1 P56817 2/20 0.50
MEN1 O00255 1/20 0.50
POLB P06746 1/20 0.50
MAPK1 P28482 1/20 0.50
KMT2A Q03164 1/20 0.50
CYP2A6 P11509 1/20 0.50
GPR84 Q9NQS5 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29355861 1.00 TYR (1.00) TYRUSP2GAAALOX15RAD51
SCHEMBL5447196 0.92 TYR (0.84) TYRUSP2GAAALOX15RAD51
Sulfuric Acid SCHEMBL23541029 0.90 TYR (0.81) TYRUSP2GAAALOX15RAD51
Sulfuric Acid SCHEMBL29374819 0.90 TYR (0.81) TYRUSP2GAAALOX15RAD51
Acetic Acid SCHEMBL23646038 0.88 TYR (0.78) TYRUSP2GAAALOX15RAD51
SCHEMBL3334895 0.84 TYR (0.71) TYRUSP2GAAALOX15RAD51
SCHEMBL1225643 0.83 TYR (0.70) TYRUSP2GAAALOX15RAD51
SCHEMBL7147902 0.82 TYR (0.68) TYRUSP2GAAALOX15RAD51
Hydrochloric Acid SCHEMBL27297304 0.81 TYR (0.68) TYRUSP2GAAALOX15RAD51
Bromide SCHEMBL27298210 0.81 TYR (0.68) TYRUSP2GAAALOX15RAD51

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 9568 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144724-A1 Mixture of at least five surfactants (I1) to (I5) WELLA GERMANY GMBH (DE) 2026-05-28 US claimed
WO-2026104266-A1 USE OF A NATURAL OCCURRING POLYPHENOL AS AN OXIDATIVE COUPLER DYE PRECURSOR IN AN OXIDATIVE HAIR COLOURING COMPOSITION WELLA GERMANY GMBH (DE) 2026-05-21 WO claimed
EP-4739272-A1 OXIDATIVE HAIR COLOURING COMPOSITION Wella Germany GmbH (DE) 2026-05-13 EP claimed
US-12622856-B2 Agent for oxidative dyeing of keratin fibers, containing isatin and at least one defined polymer HENKEL AG & CO. KGAA (DE) 2026-05-12 US claimed
EP-4731170-A1 OXIDATIVE HAIR COLOURING COMPOSITION COMPRISING A CHELANT MIXTURE Wella Germany GmbH (DE) 2026-04-29 EP claimed
EP-4262691-B1 COSMETIC COMPOSITION COMPRISING A COMBINATION OF TWO PARTICULAR COUPLERS AND N,N-DICARBOXYMETHYLGLUTAMIC ACID AND/OR ITS SALTS OREAL (FR) 2026-04-08 EP claimed
US-12564545-B2 Hair coloring compositions comprising 2-amino-1-propanol as alkalising agents WELLA GERMANY GMBH (DE) 2026-03-03 US claimed
WO-2025229086-A1 ADHESIVE COSMETIC COMPOUNDS AND USES THEREOF SKINOSIVE (FR) 2025-11-06 WO claimed
US-12344708-B2 Tissue-adhesive hydrogels POLYGANICS IP B.V. (NL) 2025-07-01 US claimed
CN-115980205-B Quantitative and/or qualitative method for simultaneously measuring 54 hair dyes in hair dye product 江苏省食品药品监督检验研究院 2025-04-22 CN claimed
EP-0446132-A1 Keratinous fibres dyeing process with 6 or 7-monohydroxyindols at acidic pH and compositions L'OREAL (FR) 1991-09-11 EP claimed
US-5034015-A Fade resistant hair dyes with better coloring ability L'OREAL (FR) 1991-07-23 US claimed
EP-0415802-A1 Keratinous fibres dyeing process with monohydroxyindole and hydroxyindole-5,6-disubstituted and composition L'OREAL (FR) 1991-03-06 EP claimed
EP-0379409-A1 Products based on polymer particles containing melanine pigments, process for their preparation, and their use, particularly cosmetically L'OREAL (FR) 1990-07-25 EP claimed
EP-0376776-A2 Process for dyeing keratinous fibres with hydroxyindole associated with quinone and 1,4-benzoquinone L'OREAL (FR) 1990-07-04 EP claimed
EP-0360638-A1 Process for dyeing keratinous fibres with an indole derivative associated with a nitrite, and composition therefor L'OREAL (FR) 1990-03-28 EP claimed
WO-1990001919-A1 POLYMERIC SKIN COLORANT THE GILLETTE COMPANY (US) 1990-03-08 WO claimed
EP-0348280-A1 Process for colouring keratinous fibres on the basis of 5,6-dihydroxy-indole or a derivative of indole and at least a salt of a rare-earth metal, and compositions for carrying out the process L'OREAL (FR) 1989-12-27 EP claimed
US-4776857-A HYDROXYINDOLES AND PERIODATE OXIDIZERS; HAIR AND SKIN REPLIGEN CORPORATION (US) 1988-10-11 US claimed
EP-0271186-A1 Hydroxyindoles and their use in dyeing REPLIGEN CORPORATION (US) 1988-06-15 EP claimed