Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 13/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 13/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2365011 | 0.85 | MTNR1A (0.51) | MTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL10884186 | 0.81 | MTNR1A (0.49) | MTNR1AMTNR1BL3MBTL1KCNN4SMN1; SMN2 | |
| SCHEMBL2729130 | 0.75 | CES1 (0.46) | KCNN4 | |
| SCHEMBL2364653 | 0.75 | MTNR1A (0.46) | MTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL28753479 | 0.74 | CES1 (0.44) | KCNN4SMN1; SMN2 | |
| SCHEMBL3363882 | 0.74 | CES1 (0.44) | KCNN4 | |
| SCHEMBL7924474 | 0.74 | CES1 (0.44) | KCNN4SMN1; SMN2 | |
| SCHEMBL6387363 | 0.74 | CYP2C19 (0.53) | KCNN4SMN1; SMN2 | |
| SCHEMBL31152049 | 0.73 | HDAC3 (0.44) | KCNN4SMN1; SMN2 | |
| SCHEMBL27276279 | 0.72 | CES1 (0.37) | L3MBTL1KCNN4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | disclosed |