Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 9/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 9/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL878149 | 0.78 | POLB (0.44) | L3MBTL1CYP1A2CNR1CNR2LMNA | |
| SCHEMBL27466589 | 0.78 | CYP1A2 (0.50) | L3MBTL1CYP1A2LMNAHTTKIF11 | |
| SCHEMBL2364636 | 0.75 | MTNR1A (0.46) | MTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL10884186 | 0.74 | MTNR1A (0.49) | MTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL3433832 | 0.73 | CYP1A2 (0.54) | L3MBTL1CYP1A2LMNAHTTKIF11 | |
| SCHEMBL2365011 | 0.73 | MTNR1A (0.51) | MTNR1AMTNR1BL3MBTL1 | |
| SCHEMBL6688205 | 0.73 | CYP1A2 (0.48) | CYP1A2CNR1CNR2KIF11 | |
| SCHEMBL6691407 | 0.73 | CYP1A2 (0.48) | CYP1A2CNR1CNR2KIF11 | |
| SCHEMBL1133623 | 0.72 | SCN5A (0.46) | CYP1A2HTTKIF11 | |
| SCHEMBL27508355 | 0.72 | SCN5A (0.46) | CYP1A2HTTKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | disclosed |