SCHEMBL2364872

SCHEMBL2364872

C=CCONC(=O)OCC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.38
ALOX15 P16050 1/20 0.38
MGAM O43451 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
MAPT P10636 3/20 0.38
TSHR P16473 2/20 0.38
CACNA1B Q00975 1/20 0.38
APBA1 Q02410 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.36
ALDH1A1 P00352 4/20 0.36
LMNA P02545 2/20 0.34
HSD17B10 Q99714 2/20 0.34
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
SOAT1 P35610 1/20 0.33
NPC1 O15118 1/20 0.33
POLB P06746 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28198217 0.85 MAPT (0.46) GAAMAPTTSHRCACNA1BAPBA1
SCHEMBL7055483 0.84 MAPT (0.42) GAAALOX15MGAMSIMGAM2
SCHEMBL17844756 0.82 GAA (0.39) GAAALOX15MGAMSIMGAM2
SCHEMBL608445 0.78
SCHEMBL6993745 0.78 MAPT (0.43) GAAMGAMSIMGAM2MAPT
SCHEMBL694328 0.76
SCHEMBL638200 0.75
SCHEMBL3053229 0.74 SMN1; SMN2 (0.41) GAAMAPTCACNA1BAPBA1SMN1; SMN2
SCHEMBL873545 0.74
SCHEMBL8522930 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1617994-B1 METHODS FOR THE ATTACHMENT OF MATERIALS TO POLYURETHANE FOAM, AND ARTICLES MADE USING THEM RYNEL INC (US) 2017-03-01 EP disclosed
WO-2016095088-A1 ERK INHIBITORS MERCK SHARP & DOHME CORP. (US) 2016-06-23 WO disclosed
US-8962027-B2 Materials comprising water-soluble polymer particles and methods of making and using them RYNEL INC. (US) 2015-02-24 US disclosed
EP-2167549-B1 MATERIALS COMPRISING WATER-SOLUBLE POLYMER PARTICLES AND METHODS OF MAKING AND USING THEM RYNEL INC (US) 2012-09-26 EP disclosed
US-8211255-B2 Apparatus and methods for the attachment of materials to polyurethane foam, and articles made using them RYNEL INC. (US) 2012-07-03 US disclosed
US-20110171282-A1 Materials Comprising Water-Soluble Polymer Particles and Methods of Making and Using Them RYNEL INC. (US) 2011-07-14 US disclosed
EP-2167549-A2 MATERIALS COMPRISING WATER-SOLUBLE POLYMER PARTICLES AND METHODS OF MAKING AND USING THEM RYNEL, INC. (US) 2010-03-31 EP disclosed
EP-1617994-A4 APPARATUS AND METHODS FOR THE ATTACHMENT OF MATERIALS TO POLYURETHANE FOAM, AND ARTICLES MADE USING THEM RYNEL INC (US) 2009-07-01 EP disclosed
WO-2009010423-A1 MULTICOMPONENT THIOL-ENE COMPOSITIONS FOR LAMINATE MATERIALS CYTEC SURFACE SPECIALTIES, S.A. (BE) 2009-01-22 WO disclosed
US-20090008021-A1 Apparatus and Methods for the Attachment of Materials to Polyurethane Foam, and Articles Made Using Them RYNEL, INC. (US) 2009-01-08 US disclosed
US-6291581-B1 RADIATION CURABLE DSM N.V. (NL) 2001-09-18 US disclosed
US-6114402-A A FOAMABLE POLYURETHANE FOR USE AS A CORE MATERIAL IN A LAMINATE FOR BONDING WITH AN UNSATURATED POLYESTER RESIN HEHR INTERNATIONAL INC. (US) 2000-09-05 US disclosed
EP-1023353-A1 POWDER PAINT BINDER COMPOSITION DSM N.V. (NL) 2000-08-02 EP disclosed
EP-0895487-A4 MODIFIED RIGID, FOAMABLE URETHANE COMPOSITION AND METHOD HEHR INTERNATIONAL INC (US) 1999-06-30 EP disclosed
WO-1999014254-A1 POWDER PAINT BINDER COMPOSITION DSM N.V. (NL) 1999-03-25 WO disclosed
EP-0895487-A1 MODIFIED RIGID, FOAMABLE URETHANE COMPOSITION AND METHOD Hehr International Inc. (US) 1999-02-10 EP disclosed
WO-1997039836-A1 MODIFIED RIGID, FOAMABLE URETHANE COMPOSITION AND METHOD HEHR INTERNATIONAL INC. (US) 1997-10-30 WO disclosed
EP-0719780-A1 Organic Phosphoric acid ester derivatives NIHON BAYER AGROCHEM K.K. (JP) 1996-07-03 EP disclosed
US-4914124-A ADMINISTERING NEMATOCIDES BAYER AKTIENGESELLSCHAFT (DE) 1990-04-03 US disclosed
US-4005041-A CLEAR VARNISH OR PIGMENTED COATING PROLUX PAINT MANUFACTURERS (PTY) LIMITED (ZA) 1977-01-25 US disclosed