Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL195968 | 0.83 | POLQ (0.45) | ALDH1A1KMT2ANPC1RAB9APOLB | |
| SCHEMBL194876 | 0.83 | MEN1 (0.62) | ALDH1A1KDM4EMEN1KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL9004750 | 0.81 | MEN1 (0.60) | ALDH1A1KDM4EMEN1KMT2ANPC1 | |
| SCHEMBL3793278 | 0.79 | POLQ (0.40) | ALDH1A1KDM4EMEN1KMT2ANPC1 | |
| SCHEMBL236493 | 0.76 | POLQ (0.38) | ALDH1A1POLBGAATDP1L3MBTL1 | |
| SCHEMBL2096212 | 0.72 | POLQ (0.44) | ALDH1A1KMT2ANPC1RAB9APOLB | |
| SCHEMBL236494 | 0.72 | POLQ (0.35) | ALDH1A1MEN1KMT2APOLBGAA | |
| SCHEMBL2583273 | 0.71 | POLQ (0.47) | ALDH1A1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL7759976 | 0.70 | MEN1 (0.68) | ALDH1A1KDM4EMEN1KMT2ANPC1 | |
| SCHEMBL1008398 | 0.69 | POLB (0.63) | ALDH1A1KDM4EMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2401276-A1 | NITROGEN-CONTAINING FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS BETA AMYLOID PRODUCTION INHIBITORS | Eisai R&D Management Co., Ltd. (JP) | 2012-01-04 | — | — | EP | disclosed |