Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.68 |
| ▸ | RAB9A | P51151 | 4/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | NPC1 | O15118 | 2/20 | 0.68 |
| ▸ | THRB | P10828 | 1/20 | 0.68 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.68 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | CDK9 | P50750 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 4/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7877742 | 0.89 | MEN1 (0.64) | MEN1KMT2ARAB9AKDM4EALDH1A1 | |
| SCHEMBL4554988 | 0.87 | KMT2A (0.69) | MEN1KMT2ARAB9AKDM4EALDH1A1 | |
| SCHEMBL13193500 | 0.87 | ALDH1A1 (0.69) | MEN1KMT2ARAB9AKDM4EALDH1A1 | |
| SCHEMBL5612816 | 0.86 | MEN1 (0.58) | MEN1KMT2ARAB9AKDM4EALDH1A1 | |
| SCHEMBL5149988 | 0.85 | MEN1 (0.63) | MEN1KMT2ARAB9AKDM4EALDH1A1 | |
| SCHEMBL24732382 | 0.85 | KDR (0.73) | MEN1KMT2ARAB9AKDM4EALDH1A1 | |
| SCHEMBL6565658 | 0.85 | TRPV1 (0.66) | MEN1KMT2ARAB9AKDM4EALDH1A1 | |
| SCHEMBL6677249 | 0.84 | SMN1; SMN2 (0.66) | MEN1KMT2ARAB9AKDM4EALDH1A1 | |
| SCHEMBL22567818 | 0.84 | KDR (0.60) | MEN1KMT2ARAB9AKDM4EALDH1A1 | |
| SCHEMBL1462231 | 0.83 | GRIK1 (0.72) | MEN1KMT2ARAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0015110-A2 | Anticoccidial composition, carbanilides and method of preparing them | ELI LILLY AND COMPANY (US) | 1980-09-03 | — | — | EP | claimed |
| US-4018888-A | Amine-stabilized dry powder aerosol antiperspirant compositions and method of preparation | THE PROCTER & GAMBLE COMPANY (US) | 1977-04-19 | — | — | US | claimed |
| US-4018887-A | Amide-stabilized dry powder aerosol antiperspirant compositions and method of preparation | THE PROCTER & GAMBLE COMPANY (US) | 1977-04-19 | — | — | US | claimed |
| US-20210046098-A1 | METHODS AND COMPOSITIONS FOR TREATING AND PREVENTING SKIN BARRIER DISRUPTIONS | DERMAFENCE LTD (IL) | 2021-02-18 | — | — | US | disclosed |
| EP-3749277-A1 | METHODS AND COMPOSITIONS FOR TREATING AND PREVENTING SKIN BARRIER DISRUPTIONS | Dermafence Ltd. (IL) | 2020-12-16 | — | — | EP | disclosed |
| US-10815335-B2 | Ring-opening polymerizations using a flow reactor | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2020-10-27 | — | — | US | disclosed |
| CN-111683643-A | Methods and compositions for treating and preventing skin barrier disruption | 德玛芬斯有限责任公司 | 2020-09-18 | — | — | CN | disclosed |
| WO-2019150375-A1 | METHODS AND COMPOSITIONS FOR TREATING AND PREVENTING SKIN BARRIER DISRUPTIONS | DERMAFENCE LTD. (IL) | 2019-08-08 | — | — | WO | disclosed |
| WO-2001080820-A2 | METHOD OF CLEANSING SKIN AND IMPROVING SKIN CARE IN BAR COMPRISING SOAP, FATTY ACID AND POLYALKYLENE GLYCOL | UNILEVER PLC (GB) | 2001-11-01 | — | — | WO | disclosed |
| WO-1999028429-A1 | CLEANSING COMPOSITION CONTAINING POLYMERIC GELLANT | BUSH BOAKE ALLEN CORPORATION (US) | 1999-06-10 | — | — | WO | disclosed |
| EP-0762868-A1 | MILD ANTIMICROBIAL LIQUID CLEANSING FORMULATIONS | UNILEVER PLC (GB) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995032705-A1 | MILD ANTIMICROBIAL LIQUID CLEANSING FORMULATIONS | UNILEVER PLC (GB) | 1995-12-07 | — | — | WO | disclosed |
| US-5103500-A | Odor suppressing disposable garment shield | NAGER FRANK B (US) | 1992-04-14 | — | — | US | disclosed |
| US-4822596-A | MOISTURE ABSORBING POLYMERS IN NONAQUEOUS LIQUID; FOR AEROSOL SPRAYING | LEVER BROTHERS COMPANY (US) | 1989-04-18 | — | — | US | disclosed |
| US-4743440-A | ANTIPERSPIRANTS, WATER ABSORBING POLYMER | LEVER BROTHERS COMPANY (US) | 1988-05-10 | — | — | US | disclosed |
| US-4650670-A | MOISTURE-ABSORBENT POLYMER | LEVER BROTHERS COMPANY (US) | 1987-03-17 | — | — | US | disclosed |
| US-4045548-A | ALUMINUM, ZIRCONIUM, OR ZINC SALTS, HYDROPHOBIC CLAYS, AND A MULTIPLE ESTER OF AN ORGANIC ACID CARRIER | THE PROCTER & GAMBLE COMPANY (US) | 1977-08-30 | — | — | US | disclosed |
| US-4018888-A | Amine-stabilized dry powder aerosol antiperspirant compositions and method of preparation | THE PROCTER & GAMBLE COMPANY (US) | 1977-04-19 | — | — | US | disclosed |
| US-4018887-A | Amide-stabilized dry powder aerosol antiperspirant compositions and method of preparation | THE PROCTER & GAMBLE COMPANY (US) | 1977-04-19 | — | — | US | disclosed |
| US-4014807-A | ALCOHOLS, DIOCTYL ADIPATE, SOAPS, DETERGENTS | HENKEL & CIE G.M.B.H. (DT) | 1977-03-29 | — | — | US | disclosed |