Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 1.00 |
| ▸ | GAA | P10253 | 5/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | THRB | P10828 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.40 |
| ▸ | MAOA | P21397 | 4/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | MGLL | Q99685 | 4/20 | 0.39 |
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9153141 | 0.98 | GAA (0.96) | ALDH1A1GAAMAPTTHRBTDP1 | |
| SCHEMBL4664754 | 0.94 | GAA (0.89) | ALDH1A1GAAMAPTTHRBTDP1 | |
| SCHEMBL15884557 | 0.85 | ALDH1A1 (0.73) | ALDH1A1GAAMAPTTHRBTDP1 | |
| SCHEMBL9069384 | 0.81 | GAA (0.68) | ALDH1A1GAAMAPTTHRBTDP1 | |
| SCHEMBL17817456 | 0.79 | ALDH1A1 (0.65) | ALDH1A1GAAMAPTTHRBMGLL | |
| SCHEMBL3269226 | 0.79 | ALDH1A1 (0.65) | ALDH1A1GAAMAPTTHRBMGLL | |
| SCHEMBL310102 | 0.78 | — | — | |
| SCHEMBL28979898 | 0.78 | GAA (0.64) | ALDH1A1GAAMAPTTHRBMGLL | |
| SCHEMBL10883416 | 0.76 | MAPT (0.61) | ALDH1A1GAAMAPTTHRBMGLL | |
| SCHEMBL11421981 | 0.76 | ALDH1A1 (0.61) | ALDH1A1GAAMAPTTHRBMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9005670-B2 | Use of histone acetyltransferase inhibitors as novel anti-cancer therapies | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-04-14 | — | — | US | disclosed |
| US-20130142887-A1 | USE OF HISTONE ACETYLTRANSFERASE INHIBITORS AS NOVEL ANTI-CANCER THERAPIES | THE JOHNS HOPKINS UNIVERSITY (US) | 2013-06-06 | — | — | US | disclosed |
| WO-2011085039-A2 | USE OF HISTONE ACETYLTRANSFERASE INHIBITORS AS NOVEL ANTI-CANCER THERAPIES | THE JOHNS HOPKINS UNIVERSITY (US) | 2011-07-14 | — | — | WO | disclosed |
| EP-1043365-B1 | Polymerizable 1,2-dipyrazolylethenes as dyes for ophthalmic plastic lenses | HOYA HEALTHCARE CORP (JP) | 2006-10-18 | — | — | EP | disclosed |
| US-6310215-B1 | EXCELLENT COPOLYMERIZABILITY AND UNDERGO NO ELUTION IN AN ORGANIC SOLVENT | HOYA HEALTHCARE CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-1043365-A1 | Polymerizable 1,2-dipyrazolylethenes as dyes for ophthalmic plastic lenses | Hoya Healthcare Corporation (JP) | 2000-10-11 | — | — | EP | disclosed |
| US-5063245-A | Hormone inhibitors | NOVA PHARMACEUTICAL CORPORATION (US) | 1991-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130142887-A1 | USE OF HISTONE ACETYLTRANSFERASE INHIBITORS AS NOVEL ANTI-CANCER THERAPIES | EP300, HDAC1, KAT2A | ALDH1A1 677/4885GAA 1800/4885MAPT 2346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.