Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | AXL | P30530 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24344343 | 0.76 | — | — | |
| SCHEMBL19099014 | 0.72 | NOS1 (0.37) | NOS1AXLNPC1RAB9AGRM2 | |
| SCHEMBL1900443 | 0.72 | CCR4 (0.40) | NOS1AXLNPC1RAB9AGRM2 | |
| SCHEMBL18993241 | 0.72 | NOS1 (0.37) | NOS1AXLNPC1RAB9AGRM2 | |
| SCHEMBL29692488 | 0.72 | CCR4 (0.40) | NOS1AXLNPC1RAB9AGRM2 | |
| SCHEMBL30975544 | 0.71 | NOS1 (0.34) | NOS1AXLNPC1RAB9AGRM2 | |
| SCHEMBL24210674 | 0.71 | NOS1 (0.34) | NOS1NPC1RAB9ABACE1ADRA2A | |
| SCHEMBL29303425 | 0.71 | NOS1 (0.34) | NOS1AXLNPC1RAB9AGRM2 | |
| SCHEMBL441028 | 0.68 | CYP1A2 (0.54) | — | |
| SCHEMBL30975428 | 0.68 | EZH2 (0.39) | NOS1AXLNPC1RAB9AGRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3406612-B1 | CARBOLINE DERIVATIVE SERVING AS BROMODOMAIN INHIBITOR | NINGBO WENDA PHARMA TECH LTD (CN) | 2021-07-21 | — | — | EP | disclosed |