Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.30 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.30 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2383365 | 0.76 | NOS1 (0.37) | NOS1MEN1NPC1LMNAGLA | |
| SCHEMBL29122301 | 0.72 | BACE1 (0.37) | NOS1MEN1NPC1LMNAGLA | |
| SCHEMBL30848040 | 0.71 | NOS1 (0.34) | NOS1MEN1NPC1LMNAGLA | |
| SCHEMBL23652343 | 0.71 | NOS1 (0.34) | NOS1NPC1RAB9ABACE1ADRA2A | |
| SCHEMBL22732177 | 0.69 | KDM4E (0.39) | MEN1LMNAKMT2A | |
| SCHEMBL4083412 | 0.68 | NOS1 (0.34) | NOS1MEN1NPC1LMNAGLA | |
| SCHEMBL31582950 | 0.68 | PLA2G1B (0.37) | NOS1MEN1NPC1LMNAGLA | |
| SCHEMBL31130304 | 0.68 | GRM2 (0.44) | NOS1MEN1NPC1KMT2AADRA2A | |
| SCHEMBL31038901 | 0.67 | ADRA2A (0.35) | NOS1MEN1NPC1LMNAGLA | |
| SCHEMBL31440065 | 0.65 | CSNK2A2 (0.37) | NPC1LMNARAB9AKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022012534-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION, AND APPLICATIONS | 广州费米子科技有限责任公司 | 2022-01-20 | — | — | WO | disclosed |