Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.41 |
| ▸ | DAO | P14920 | 3/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.39 |
| ▸ | GUSB | P08236 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | CLK1 | P49759 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5318244 | 0.78 | KDM4E (0.42) | PARP1KDM4EHCAR1DAOMAPKAPK2 | |
| SCHEMBL30297078 | 0.78 | CA12 (0.50) | CA12CA9PARP1KDM4EHCAR1 | |
| SCHEMBL1043395 | 0.78 | MAPKAPK2 (0.39) | PARP1KDM4EDAOMAPKAPK2RPS6KA3 | |
| SCHEMBL30297088 | 0.78 | CA12 (0.50) | CA12CA9PARP1KDM4EHCAR1 | |
| SCHEMBL2800776 | 0.78 | CA12 (0.50) | CA12CA9KDM4EHCAR1DAO | |
| SCHEMBL17844981 | 0.74 | RXFP1 (0.44) | CA12CA9KDM4EHCAR1DAO | |
| SCHEMBL9039429 | 0.74 | ALDH1A1 (0.43) | KDM4EHCAR1MAPKAPK2RPS6KA3CSNK2A1 | |
| SCHEMBL22654726 | 0.74 | UPP1 (0.40) | KDM4EMAPKAPK2RPS6KA3CSNK2A1PLK3 | |
| SCHEMBL15935194 | 0.74 | KIF11 (0.40) | PARP1KDM4EHCAR1MAPKAPK2RPS6KA3 | |
| SCHEMBL1041178 | 0.74 | NQO2 (0.50) | KDM4EHCAR1DAOPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3604288-B1 | REGIOSELECTIVE ONE-STEP PROCESS FOR SYNTHESIZING 2-HYDROXYQUINOXALINE | DEV CT BIOTECHNOLOGY (TW) | 2024-04-10 | — | — | EP | disclosed |
| CN-110483421-B | Preparation method of quinoxalinone derivative | 沈阳师范大学 | 2022-06-10 | — | — | CN | disclosed |
| CN-110790713-B | Regioselective one-step process for the synthesis of 2-hydroxyquinoxaline | 财团法人生物技术开发中心 | 2021-03-05 | — | — | CN | disclosed |
| CN-110790713-A | Regioselective one-step process for the synthesis of 2-hydroxyquinoxaline | 财团法人生物技术开发中心 | 2020-02-14 | — | — | CN | disclosed |
| EP-3604288-A1 | REGIOSELECTIVE ONE-STEP PROCESS FOR SYNTHESIZING 2-HYDROXYQUINOXALINE | Development Center for Biotechnology (TW) | 2020-02-05 | — | — | EP | disclosed |
| EP-3604288-A1 | REGIOSELECTIVE ONE-STEP PROCESS FOR SYNTHESIZING 2-HYDROXYQUINOXALINE | Development Center for Biotechnology (TW) | 2020-02-05 | — | — | EP | disclosed |
| EP-2352725-A1 | QUINOXALINE-BASED LXR MODULATORS | Wyeth LLC (US) | 2011-08-10 | — | — | EP | disclosed |
| WO-2010054229-A1 | QUINOXALINE-BASED LXR MODULATORS | WYETH LLC (US) | 2010-05-14 | — | — | WO | disclosed |
| US-20100120778-A1 | QUINOXALINE-BASED LXR MODULATORS | WYETH (US) | 2010-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120778-A1 | QUINOXALINE-BASED LXR MODULATORS | NR1H2, NR1H3, NR1H4 | CA12 4778/4885CA9 3174/4885PARP1 4063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.