Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.43 |
| ▸ | CLK1 | P49759 | 1/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 7/20 | 0.42 |
| ▸ | WNT3A | P56704 | 7/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10282948 | 0.89 | PRKCI (0.47) | DYRK1ACLK1DYRK1BPRKCI | |
| SCHEMBL5584643 | 0.89 | QDPR (0.45) | DYRK1ACLK1DYRK1BCTNNB1WNT3A | |
| SCHEMBL5584639 | 0.89 | NOTUM (0.40) | DYRK1ACLK1DYRK1BCTNNB1WNT3A | |
| SCHEMBL15839854 | 0.86 | L3MBTL1 (0.41) | DYRK1ACLK1DYRK1BCTNNB1WNT3A | |
| SCHEMBL13061962 | 0.81 | PRKCI (0.44) | DYRK1ACLK1DYRK1BPRKCI | |
| SCHEMBL5584893 | 0.78 | DYRK1A (0.42) | DYRK1ADYRK1BPRKCI | |
| SCHEMBL2711041 | 0.78 | QDPR (0.47) | DYRK1APRKCIL3MBTL1ESR1ESR2 | |
| SCHEMBL20656971 | 0.78 | PRKCI (0.41) | DYRK1ACLK1DYRK1BCTNNB1WNT3A | |
| SCHEMBL20656972 | 0.78 | PRKCI (0.41) | DYRK1ACLK1DYRK1BCTNNB1WNT3A | |
| SCHEMBL14046556 | 0.77 | QDPR (0.51) | PRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3851436-A1 | NOVEL HETEROAROMATIC AMIDE DERIVATIVE AND MEDICINE CONTAINING SAME | Kaken Pharmaceutical Co., Ltd. (JP) | 2021-07-21 | — | — | EP | disclosed |