Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23996915 | 0.82 | ALDH1A1 (0.32) | MAPTRAB9A | |
| SCHEMBL23652885 | 0.79 | POLB (0.37) | MAPTKMT2AMEN1TDP1 | |
| SCHEMBL31121984 | 0.79 | PARG (0.47) | — | |
| SCHEMBL17845472 | 0.79 | PARG (0.47) | — | |
| SCHEMBL23996891 | 0.78 | BCL2 (0.32) | BCL2MAPTRAB9AL3MBTL1GSK3B | |
| SCHEMBL23652896 | 0.78 | MAPT (0.46) | MAPTKMT2AMEN1MAPK1 | |
| SCHEMBL23652899 | 0.78 | L3MBTL1 (0.49) | MAPTL3MBTL1KMT2AMEN1MAPK1 | |
| SCHEMBL23652707 | 0.74 | PARG (0.33) | MAPTRAB9AKMT2AMEN1MAPK1 | |
| SCHEMBL23653348 | 0.74 | ALDH1A1 (0.33) | KMT2AMEN1 | |
| SCHEMBL23653364 | 0.73 | ALDH1A1 (0.44) | MAPTRAB9AKMT2AMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233845-B1 | PARG INHIBITORY COMPOUNDS | CANCER RESEARCH TECH LTD (GB) | 2021-07-21 | — | — | EP | disclosed |