Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR4 | P22455 | 14/20 | 0.66 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.42 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.42 |
| ▸ | SYK | P43405 | 5/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16071409 | 0.86 | FGFR4 (0.88) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL24225084 | 0.80 | FGFR4 (0.73) | FGFR4 | |
| SCHEMBL17974120 | 0.80 | FGFR4 (0.90) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL19801113 | 0.80 | FGFR4 (1.00) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL19069269 | 0.79 | FGFR4 (0.93) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL18897178 | 0.78 | FGFR4 (0.53) | FGFR4SYK | |
| SCHEMBL18897242 | 0.78 | FGFR4 (0.78) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL18897164 | 0.77 | FGFR4 (0.56) | FGFR4 | |
| SCHEMBL16071415 | 0.77 | FGFR4 (1.00) | FGFR4FGFR1FGFR2FGFR3 | |
| SCHEMBL16137280 | 0.76 | FGFR4 (0.87) | FGFR4FGFR1FGFR2FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968337-B1 | HETEROARYL COMPOUNDS AND USES THEREOF | CELGENE CAR LLC (BM) | 2021-07-21 | — | — | EP | disclosed |