Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22562890 | 0.92 | BCL2 (0.69) | BCL2 | |
| SCHEMBL21573218 | 0.89 | BCL2 (0.71) | BCL2 | |
| SCHEMBL22562926 | 0.88 | BCL2 (0.64) | BCL2 | |
| SCHEMBL19854194 | 0.87 | BCL2 (0.69) | BCL2 | |
| SCHEMBL22562899 | 0.85 | BCL2 (0.69) | BCL2 | |
| SCHEMBL29376973 | 0.84 | BCL2 (0.82) | BCL2 | |
| SCHEMBL20580518 | 0.84 | BCL2 (0.82) | BCL2 | |
| SCHEMBL19853626 | 0.83 | BCL2 (0.69) | BCL2 | |
| SCHEMBL19853741 | 0.83 | BCL2 (0.82) | BCL2 | |
| SCHEMBL19853634 | 0.83 | BCL2 (0.80) | BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3672595-B1 | COMBINATION PRODUCT OF BCL-2 INHIBITOR AND CHEMOTHERAPEUTIC AGENT AND USE THEREOF IN THE PREVENTION AND/OR TREATMENT OF DISEASES | ASCENTAGE PHARMA SUZHOU CO LTD (CN) | 2021-07-21 | — | — | EP | disclosed |