Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGAV | P06756 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12288118 | 1.00 | CES2 (0.50) | CES2MEN1KMT2AGAAHTT | |
| SCHEMBL21074459 | 0.88 | CES2 (0.39) | CES2MEN1KMT2AGAAHTT | |
| SCHEMBL15761103 | 0.83 | CES2 (0.50) | CES2MEN1KMT2AGAANOTUM | |
| SCHEMBL13284188 | 0.83 | CES2 (0.50) | CES2MEN1KMT2AGAANOTUM | |
| SCHEMBL17899795 | 0.80 | KMT2A (0.62) | CES2MEN1KMT2AGAAHTT | |
| SCHEMBL6819613 | 0.78 | CES2 (0.45) | CES2MEN1KMT2AGAANOTUM | |
| SCHEMBL4947449 | 0.77 | CES2 (0.59) | CES2MEN1KMT2AGAANOTUM | |
| SCHEMBL25658887 | 0.77 | CES2 (0.48) | CES2KMT2AGAAHTTCTSL | |
| SCHEMBL15561973 | 0.77 | CES2 (0.58) | CES2MEN1KMT2AGAANOTUM | |
| SCHEMBL13925972 | 0.75 | CES2 (0.56) | CES2GAANOTUMMAPTRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2363388-A1 | Process for the production of chiral amines | DSM IP Assets B.V. (NL) | 2011-09-07 | — | — | EP | disclosed |