SCHEMBL23656346

SCHEMBL23656346

C/C=C\C=C(/C)N(c1ccc(N(c2ccc(N(c3ccccc3)c3cccc(C)c3)cc2)c2ccc(N(c3ccccc3)c3cccc(C)c3)cc2)cc1)c1cccc(C)c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGIR P43119 3/20 0.34
CYP3A4 P08684 2/20 0.34
CYP2C9 P11712 2/20 0.34
CYP2C19 P33261 2/20 0.34
ALDH1A1 P00352 6/20 0.33
NPC1 O15118 3/20 0.33
RAB9A P51151 3/20 0.33
PAX8 Q06710 2/20 0.33
PKM P14618 2/20 0.33
JAK2 O60674 1/20 0.33
HTT P42858 1/20 0.33
THRB P10828 1/20 0.33
HPGD P15428 3/20 0.32
TP53 P04637 1/20 0.32
GPX4 P36969 1/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
APAF1 O14727 1/20 0.32
TDP2 O95551 1/20 0.32
NFKB1 P19838 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22876500 0.89 ALDH1A1 (0.38) CYP3A4CYP2C9CYP2C19ALDH1A1NPC1
SCHEMBL14040217 0.85 PTGIR (0.34) PTGIRALDH1A1NPC1RAB9APAX8
SCHEMBL19466009 0.85 TP53 (0.33) PTGIRCYP3A4CYP2C9CYP2C19ALDH1A1
SCHEMBL20019074 0.84 ALDH1A1 (0.35) CYP3A4CYP2C9CYP2C19ALDH1A1HPGD
SCHEMBL10062047 0.84 HSD17B1 (0.34) PTGIRALDH1A1NPC1RAB9APAX8
SCHEMBL21029199 0.82 NPSR1 (0.40) ALDH1A1NPC1RAB9AHTTHPGD
SCHEMBL19285906 0.82 ALDH1A1 (0.35) ALDH1A1HTTTP53MEN1KMT2A
SCHEMBL19061202 0.82 TP53 (0.33) PTGIRALDH1A1NPC1RAB9APAX8
SCHEMBL21335349 0.82 HSD17B1 (0.33) PTGIR
SCHEMBL23393456 0.82 HSD17B1 (0.33) PTGIRCYP3A4CYP2C9CYP2C19TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3851443-B1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2023-09-13 EP disclosed
EP-3851443-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING ORGANOMETALLIC COMPOUND, AND ELECTRONIC APPARATUS INCLUDING ORGANIC LIGHT-EMITTING DEVICE Samsung Electronics Co., Ltd. (KR) 2021-07-21 EP disclosed