Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.51 |
| ▸ | BCL2 | P10415 | 5/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23657342 | 0.90 | HRH3 (0.50) | HRH3BCL2BCHEACHEMEN1 | |
| SCHEMBL23657302 | 0.89 | TSHR (0.57) | TSHRUSP2ALOX15MAPK1HSD17B10 | |
| SCHEMBL23657212 | 0.86 | HRH3 (0.55) | HRH3ALDH1A1CACNA1B | |
| SCHEMBL4966805 | 0.80 | TP53 (0.63) | BCHEACHETSHRMAPK1ALDH1A1 | |
| SCHEMBL23657403 | 0.80 | HRH3 (0.54) | HRH3ALDH1A1CACNA1B | |
| SCHEMBL23649328 | 0.79 | TBXA2R (0.54) | HRH3BCL2TSHRALDH1A1CACNA1H | |
| SCHEMBL23657190 | 0.78 | MAPT (0.54) | MEN1NPC1RAB9AKMT2AALDH1A1 | |
| SCHEMBL23928183 | 0.77 | HRH3 (0.63) | HRH3MEN1NPC1RAB9AKMT2A | |
| SCHEMBL7165188 | 0.76 | KDM4E (0.68) | BCHEACHETSHRALDH1A1HTT | |
| SCHEMBL1981044 | 0.73 | PKM (0.62) | HRH3BCHEACHETSHRUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021145729-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF | DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION (KR) | 2021-07-22 | — | — | WO | disclosed |