Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.54 |
| ▸ | LSS | P48449 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | DRD4 | P21917 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23657212 | 0.94 | HRH3 (0.55) | HRH3LSSLTA4HCACNA1BKDM4E | |
| SCHEMBL23657277 | 0.80 | HRH3 (0.51) | HRH3CACNA1BALDH1A1 | |
| SCHEMBL23657209 | 0.80 | PTGES (0.47) | LSSDRD2DRD4DRD3LTA4H | |
| SCHEMBL11264560 | 0.79 | HRH3 (0.77) | HRH3LSSLTA4HCACNA1BSIGMAR1 | |
| SCHEMBL23657359 | 0.79 | SLC6A4 (0.58) | — | |
| SCHEMBL23657362 | 0.78 | HTR5A (0.53) | HRH3LSSKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL23657342 | 0.77 | HRH3 (0.50) | HRH3ALDH1A1SMN1; SMN2 | |
| SCHEMBL18573441 | 0.76 | NPC1 (0.45) | SIGMAR1KDM4EALDH1A1 | |
| SCHEMBL23649334 | 0.76 | ALDH1A1 (0.60) | HRH3LSSCACNA1BSIGMAR1ALDH1A1 | |
| SCHEMBL11508349 | 0.75 | BCHE (0.63) | HRH3LSSDRD4LTA4HCACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021145729-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF | DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION (KR) | 2021-07-22 | — | — | WO | disclosed |