Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 9/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | SNCA | P37840 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23657181 | 0.95 | HTR1A (0.55) | HTR1ADRD3DRD2HTR6KCNA5 | |
| SCHEMBL23657413 | 0.92 | HTR1A (0.52) | HTR1ADRD3DRD2HTR6KCNA5 | |
| SCHEMBL23657289 | 0.91 | HTR1A (0.49) | HTR1ADRD3DRD2KCNA5KCNH2 | |
| SCHEMBL23657372 | 0.89 | HTR1A (0.54) | HTR1ADRD3DRD2KCNA5KCNH2 | |
| SCHEMBL23657418 | 0.88 | HTR1A (0.62) | HTR1AHTR2A | |
| SCHEMBL23657456 | 0.87 | HTR1A (0.50) | HTR1AHTR6KCNH2 | |
| SCHEMBL23657349 | 0.87 | HTR1A (0.53) | HTR1ADRD3DRD2KCNH2ACHE | |
| SCHEMBL23657180 | 0.87 | HTR1A (0.51) | HTR1ADRD3DRD2KCNA5KCNH2 | |
| SCHEMBL23657334 | 0.86 | HTR1A (0.52) | HTR1ADRD3DRD2KCNA5KCNH2 | |
| SCHEMBL23657266 | 0.85 | KCNA5 (0.64) | HTR1AKCNA5KCNH2ACHEHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021145729-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF | DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION (KR) | 2021-07-22 | — | — | WO | disclosed |