Barbital

Barbital

SCHEMBL236590

CCC1(CC)C(=O)NC(=O)NC1=O.[NaH]

nearest known ligand 0.94

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.94
ALDH1A1 P00352 4/20 0.48
TP53 P04637 1/20 0.45
KDM4E B2RXH2 1/20 0.43
CYP3A4 P08684 1/20 0.43
GABRB3 P28472 1/20 0.43
OPRD1 P41143 1/20 0.43
GABRA2 P47869 1/20 0.43
GABRB2 P47870 1/20 0.43
HSD17B10 Q99714 1/20 0.41
MMP2 P08253 5/20 0.39
MMP9 P14780 5/20 0.39
MMP8 P22894 4/20 0.39
MMP13 P45452 4/20 0.39
MMP3 P08254 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
TSHR P16473 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Barbital SCHEMBL11212132 1.00 LMNA (0.94) LMNAALDH1A1TP53KDM4ECYP3A4
Barbital SCHEMBL27508367 0.97 LMNA (0.90) LMNAALDH1A1TP53KDM4ECYP3A4
Barbital SCHEMBL43818 0.97 LMNA (1.00) LMNAALDH1A1TP53KDM4ECYP3A4
Barbital SCHEMBL3859278 0.97 LMNA (1.00) LMNAALDH1A1TP53KDM4ECYP3A4
Barbital SCHEMBL8746543 0.95 LMNA (0.85) LMNAALDH1A1TP53KDM4ECYP3A4
Barbital SCHEMBL23533431 0.94 LMNA (0.94) LMNAALDH1A1TP53KDM4ECYP3A4
Barbital SCHEMBL11328256 0.94 LMNA (0.94) LMNAALDH1A1TP53KDM4ECYP3A4
Barbital SCHEMBL7592317 0.94 LMNA (0.94) LMNAALDH1A1TP53KDM4ECYP3A4
Barbital SCHEMBL2128102 0.94 LMNA (0.94) LMNAALDH1A1TP53KDM4ECYP3A4
Barbital SCHEMBL11328233 0.94 LMNA (0.94) LMNAALDH1A1TP53KDM4ECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3187 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122063168-A Ion detection module and preparation method thereof 中国科学院上海微系统与信息技术研究所 2026-05-19 CN claimed
US-12529628-B2 Microbeads and preparation method therefor LG CHEM, LTD. (KR) 2026-01-20 US claimed
US-12473580-B1 One-step method for synthesizing amoxicillin from penicillin or salt thereof through enzyme catalysis XINGZHI COLLEGE ZHEJIANG NORMAL UNIVERSITY (CN) 2025-11-18 US claimed
US-12298280-B2 Method for increasing number of proteins identified by mass spectrometry PROTEINT (TIANJIN) BIOTECHNOLOGY CO., LTD (CN) 2025-05-13 US claimed
CN-115856280-B Interleukin detection kit and method for optimizing mixture ratio of capturing microsphere antibody thereof 青岛瑞斯凯尔生物科技股份有限公司 2025-04-25 CN claimed
EP-4507722-A1 NANOEMULSION UNIVERSAL INFLUENZA VACCINE Bluewillow Biologics, Inc. (US) 2025-02-19 EP claimed
CN-119335171-A Novel super living body S staining solution 吉林省众驰医疗科技有限公司 2025-01-21 CN claimed
US-12173345-B2 Ketoreductase mutant and method for producing chiral alcohols ASYMCHEM LABORATORIES (TIANJIN) CO., LTD. (CN) 2024-12-24 US claimed
CN-119092934-A Chelate modified polyolefin diaphragm and preparation method and application thereof 浙江大学杭州国际科创中心 2024-12-06 CN claimed
CN-118872666-A Clinical-grade exosome activity cryoprotectant 山东省齐鲁细胞治疗工程技术有限公司 2024-11-01 CN claimed
WO-1988001384-A1 INDICATOR DEVICE BARNARD, ERIC, EDWARD (GB) 1988-02-25 WO claimed
CN-87105619-A INDICATOR DEVICE 1988-02-24 CN claimed
EP-0122742-B1 AN AGROSE GEL ELECTROPHORESIS TECHNIQUE FOR THE DETERMINATION OF AMYLASE ISOENZYMES RUSH-PRESBYTERIAN-ST.LUKE'S MEDICAL CENTER (US) 1987-07-29 EP claimed
US-4559120-A Agarose gel electrophoresis technique for the determination of amylase isoenzymes RUSH-PRESBYTERIAN-ST. LUKE'S MEDICAL CENTER (US) 1985-12-17 US claimed
EP-0122742-A2 An agrose gel electrophoresis technique for the determination of amylase isoenzymes RUSH-PRESBYTERIAN-ST.LUKE'S MEDICAL CENTER (US) 1984-10-24 EP claimed
US-4390630-A ANTICOAGULANT THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1983-06-28 US claimed
WO-1982002600-A1 IMPROVED ELECTROPHORETIC TECHNIQUE FOR SEPARATING LACTATE DEHYDROGENASE ISOENZYMES AND IMPROVED ELECTROPHORETIC GEL FOR USE THEREIN BECKMAN INSTRUMENTS INC (US) 1982-08-05 WO claimed
US-4321121-A Electrophoretic technique for separating lactate dehydrogenase isoenzymes and improved electrophoretic gel for use therein BECKMAN INSTRUMENTS, INC. (US) 1982-03-23 US claimed
US-4246084-A BARBITAL AND GLYCINE-TYPE BUFFERS ENHANCE THE DIAGNOSTIC USEFULNESS BECKMAN INSTRUMENTS, INC. (US) 1981-01-20 US claimed
US-3995019-A FOR RADIOIMMUNOASSAY CONSISTING OF A SPECIFIC ANTIBODY RADIOLABELED, ANTIGEN, POLYETHYLENE GLYCOL, AND GAMMA GLOBULIN BAXTER TRAVENOL LABORATORIES, INC. (US) 1976-11-30 US claimed