Barbital

Barbital

SCHEMBL43818

CCC1(CC)C(=O)NC(=O)NC1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 1.00
ALDH1A1 P00352 4/20 0.50
TP53 P04637 1/20 0.46
KDM4E B2RXH2 1/20 0.45
CYP3A4 P08684 1/20 0.45
GABRB3 P28472 1/20 0.45
OPRD1 P41143 1/20 0.45
GABRA2 P47869 1/20 0.45
GABRB2 P47870 1/20 0.45
HSD17B10 Q99714 1/20 0.42
MMP2 P08253 5/20 0.40
MMP9 P14780 5/20 0.40
MMP8 P22894 4/20 0.40
MMP13 P45452 4/20 0.40
MMP3 P08254 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
TSHR P16473 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Barbital SCHEMBL3859278 1.00 LMNA (1.00) LMNAALDH1A1TP53KDM4ECYP3A4
Barbital SCHEMBL236590 0.97 LMNA (0.94) LMNAALDH1A1TP53KDM4ECYP3A4
Barbital SCHEMBL2128102 0.97 LMNA (0.94) LMNAALDH1A1TP53KDM4ECYP3A4
Barbital SCHEMBL11328233 0.97 LMNA (0.94) LMNAALDH1A1TP53KDM4ECYP3A4
Barbital SCHEMBL21084955 0.97 LMNA (0.94) LMNAALDH1A1TP53KDM4ECYP3A4
Barbital SCHEMBL23533431 0.97 LMNA (0.94) LMNAALDH1A1TP53KDM4ECYP3A4
Barbital SCHEMBL11328256 0.97 LMNA (0.94) LMNAALDH1A1TP53KDM4ECYP3A4
Barbital SCHEMBL11332231 0.97 LMNA (0.94) LMNAALDH1A1TP53KDM4ECYP3A4
Barbital SCHEMBL21084914 0.97 LMNA (0.94) LMNAALDH1A1TP53KDM4ECYP3A4
Barbital SCHEMBL7592317 0.97 LMNA (0.94) LMNAALDH1A1TP53KDM4ECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 16228 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122042861-A High-throughput screening and quantifying method for anesthetic in aquatic product based on high-resolution mass spectrum 江苏省药品监督检验研究院 2026-05-15 CN claimed
EP-4719552-A1 INDUCTION OF GENERAL ANESTHESIA IN ADULTS UNDERGOING ELECTIVE SURGERY Xizang Haisco Pharmaceutical Co., Ltd. (CN) 2026-04-08 EP claimed
US-20260008891-A1 RUBBER FILLER, RUBBER COMPOSITE COMPRISING THE SAME, AND PREPARATION METHOD THEREFOR AND USE THEREOF PETROCHINA CO LTD (CN) 2026-01-08 US claimed
US-20260007615-A1 PARTICLES COMPRISING A THERAPEUTIC OR DIAGNOSTIC AGENT AND SUSPENSIONS AND METHODS OF USE THEREOF ELEKTROFI INC (US) 2026-01-08 US claimed
EP-4659014-A1 EMULSION-BASED THICK-FILM ANTIFOULING COATING FOR HIGHLY SENSITIVE ELECTROCHEMICAL SENSING President And Fellows Of Harvard College (US) 2025-12-10 EP claimed
EP-2234598-B1 PHARMACEUTICAL COMPOSITIONS CONTAINING AT LEAST ONE PROTEINACEOUS ACTIVE INGREDIENT PROTECTED AGAINST DIGESTIVE ENZYMES BENNIS FARID (MA) 2025-11-19 EP claimed
EP-4642956-A1 ON-DEMAND NITRIC OXIDE GENERATION AND DELIVERY DEVICES Nanjing Novlead Biotechnology Co., Ltd. (CN) 2025-11-05 EP claimed
US-12440603-B2 Nerve grafts and methods of preparation thereof AXOGEN CORPORATION (US) 2025-10-14 US claimed
US-12444617-B2 Semiconductor wafer processing liquid containing hypobromite ions and PH buffering agent TOKUYAMA CORPORATION (JP) 2025-10-14 US claimed
US-20250312297-A1 REDUCTION OF HEALTHCARE RESOURCE UTILIZATION BY PATIENTS TREATED WITH INTRANASALLY-ADMINISTERED METOCLOPRAMIDE EVOKE PHARMA, INC. 2025-10-09 US claimed
US-4086059-A COMPETITIVE BINDING, ACIDIFICATION BIO-RAD LABORATORIES, INC. (US) 1978-04-25 US claimed
US-4072712-A FROM ISOCYANATES, CATALYSIS BAYER AKTIENGESELLSCHAFT (DT) 1978-02-07 US claimed
US-4062936-A BLOOD CELLS BOUND TO TANNIC ACID MOCHIDA SEIYAKU KABUSHIKI KAISHA (JA) 1977-12-13 US claimed
US-4036823-A Barbituric acid antigenic conjugates, their preparation, antibodies and use BIOLOGICAL DEVELOPMENTS, INC. (US) 1977-07-19 US claimed
US-3996162-A INORGANIC CRYSTALLINE LATTICE MATERIAL NUCLEAR MEDICAL LABORATORIES, INC. (US) 1976-12-07 US claimed
US-3995019-A FOR RADIOIMMUNOASSAY CONSISTING OF A SPECIFIC ANTIBODY RADIOLABELED, ANTIGEN, POLYETHYLENE GLYCOL, AND GAMMA GLOBULIN BAXTER TRAVENOL LABORATORIES, INC. (US) 1976-11-30 US claimed
US-3960757-A HYDROPHOBIC TOYO JOZO CO., LTD. (JA) 1976-06-01 US claimed
US-3960669-A Urine diagnostic test for fibrinolytic activity ASSOCIATION FOR PHARMACOLOGIC RESEARCH, INC. (US) 1976-06-01 US claimed
US-3960492-A Method for determining an index of binding protein content of blood NUCLEAR DIAGNOSTICS, INC. (US) 1976-06-01 US claimed
US-3941564-A Method for assessing thyroid function MILES LABORATORIES, INC. (US) 1976-03-02 US claimed