Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 7/20 | 0.44 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21887220 | 0.83 | PTPN11 (0.46) | PTPN11KCNH2KDM1A | |
| SCHEMBL21845236 | 0.83 | PTPN11 (0.49) | PTPN11KCNH2SIGMAR1 | |
| SCHEMBL21887245 | 0.78 | PTPN11 (0.46) | PTPN11KCNH2 | |
| SCHEMBL29992973 | 0.73 | PTPN11 (0.41) | PTPN11KCNH2KDM1ASIGMAR1 | |
| SCHEMBL22393543 | 0.72 | PTPN11 (0.37) | PTPN11KCNH2 | |
| SCHEMBL22393784 | 0.68 | PTPN11 (0.31) | PTPN11 | |
| SCHEMBL21887272 | 0.68 | ADRA2A (0.33) | PTPN11 | |
| SCHEMBL22393732 | 0.68 | PTPN11 (0.31) | PTPN11 | |
| SCHEMBL21845164 | 0.67 | NOS3 (0.35) | PTPN11OPRL1 | |
| SCHEMBL23562409 | 0.67 | PTPN11 (0.38) | PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021143680-A1 | HETEROARYL DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 浙江海正药业股份有限公司 | 2021-07-22 | — | — | WO | disclosed |