Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CPS1 | P31327 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GBA1 | P04062 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2366072 | 1.00 | HTT (0.40) | HTTKMT2AIDH1KDM4ECPS1 | |
| Hydrochloric Acid SCHEMBL2546014 | 0.99 | HTT (0.39) | HTTKMT2AIDH1KDM4ECPS1 | |
| Hydrochloric Acid SCHEMBL2546017 | 0.99 | HTT (0.39) | HTTKMT2AIDH1KDM4ECPS1 | |
| SCHEMBL2366672 | 0.93 | GBA1 (0.37) | HTTKMT2AIDH1KDM4ELMNA | |
| SCHEMBL2366667 | 0.93 | GBA1 (0.37) | HTTKMT2AIDH1KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL2366073 | 0.87 | SLC6A9 (0.34) | IDH1GBA1 | |
| Hydrochloric Acid SCHEMBL2366080 | 0.87 | SLC6A9 (0.34) | IDH1GBA1 | |
| SCHEMBL15015187 | 0.87 | ALDH1A1 (0.40) | HTTKMT2AKDM4ELMNAMAPT | |
| SCHEMBL2366827 | 0.86 | IDH1 (0.42) | HTTKMT2AIDH1KDM4EMAPT | |
| SCHEMBL2366562 | 0.86 | IDH1 (0.40) | HTTKMT2AIDH1KDM4ECPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364975-B1 | NOVEL AMIDE DERIVATIVE AND USE THEREOF AS MEDICINE | MITSUBISHI TANABE PHARMA CORP (JP) | 2013-06-12 | — | — | EP | disclosed |
| EP-2364975-A1 | NOVEL AMIDE DERIVATIVE AND USE THEREOF AS MEDICINE | Mitsubishi Tanabe Pharma Corporation (JP) | 2011-09-14 | — | — | EP | disclosed |