Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28121398 | 0.79 | PKM (0.43) | PKMALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL3436871 | 0.75 | PKM (0.45) | PKMALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL2611106 | 0.71 | PKM (0.45) | PKMALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL2611143 | 0.71 | PKM (0.45) | PKMALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL21093429 | 0.71 | LMNA (0.44) | PKMALDH1A1MAPTADORA2AADORA2B | |
| SCHEMBL25421142 | 0.69 | PKM (0.44) | PKMALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL1241627 | 0.69 | PKM (0.47) | PKMALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL25421838 | 0.69 | PKM (0.44) | PKMALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL17236118 | 0.69 | PKM (0.44) | PKMALDH1A1NPC1RAB9AMAPT | |
| SCHEMBL25320046 | 0.69 | MAPT (0.46) | PKMALDH1A1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021143677-A1 | FUSED RING SUBSTITUTED AROMATIC COMPOUND AND PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION, AND USE THEREOF | 青岛清原化合物有限公司 | 2021-07-22 | — | — | WO | disclosed |