SCHEMBL23665367

SCHEMBL23665367

Cc1c2nsnc2c(C)c2nc(-c3ccccc3)c(-c3ccccc3)nc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.44
ALDH1A1 P00352 5/20 0.42
KDM4E B2RXH2 5/20 0.42
L3MBTL1 Q9Y468 3/20 0.42
POLB P06746 2/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
MAPT P10636 1/20 0.42
PKM P14618 1/20 0.42
RAB9A P51151 1/20 0.42
DHFR P00374 1/20 0.40
PIK3CG P48736 1/20 0.40
HPGD P15428 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
AKT1 P31749 1/20 0.39
AKT2 P31751 1/20 0.39
LMNA P02545 2/20 0.38
HTT P42858 2/20 0.38
TP53 P04637 1/20 0.38
MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25748507 0.90 TDP1 (0.38) TDP1ALDH1A1KDM4EL3MBTL1POLB
SCHEMBL23665391 0.85 TDP1 (0.34) TDP1ALDH1A1KDM4EL3MBTL1POLB
SCHEMBL23665432 0.85 TDP1 (0.34) TDP1ALDH1A1KDM4EL3MBTL1POLB
SCHEMBL25421644 0.78 MEN1 (0.46) TDP1ALDH1A1KDM4EL3MBTL1POLB
SCHEMBL13555444 0.78 DHFR (0.41) TDP1ALDH1A1KDM4EL3MBTL1POLB
SCHEMBL11980224 0.77 DHFR (0.40) TDP1ALDH1A1KDM4EL3MBTL1POLB
SCHEMBL24012395 0.77 KDM4E (0.40) TDP1ALDH1A1KDM4EL3MBTL1MEN1
SCHEMBL18162422 0.76 TDP1 (0.47) TDP1ALDH1A1KDM4EL3MBTL1POLB
SCHEMBL21202691 0.76 ALDH1A1 (0.39) TDP1ALDH1A1KDM4EL3MBTL1POLB
SCHEMBL25450878 0.75 TDP1 (0.37) TDP1ALDH1A1KDM4EL3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023100844-A1 COMPOUND AND PHOTOELECTRIC CONVERSION ELEMENT EMPLOYING SAME 住友化学株式会社 2023-06-08 WO disclosed
US-20220416167-A1 OSMIUM-CONTAINING CONJUGATED POLYMER AND METHODS THEREOF XIAMEN UNIVERSITY (CN) 2022-12-29 US disclosed
WO-2021143690-A1 OSMIUM-CONTAINING CONJUGATED POLYMER, PREPARATION METHOD THEREFOR AND USE THEREOF 厦门大学 2021-07-22 WO disclosed