SCHEMBL23665463

SCHEMBL23665463

Cc1ccc2c3ccc(C)cc3n(C3CCCCO3)c2c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD4 P21917 1/20 0.37
CYP4F2 P78329 2/20 0.36
CYP4A11 Q02928 2/20 0.36
KDM4E B2RXH2 5/20 0.36
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
POLB P06746 1/20 0.35
HSD17B10 Q99714 5/20 0.34
TP53 P04637 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
HTR1A P08908 1/20 0.34
ADRA2A P08913 1/20 0.34
CHRM1 P11229 1/20 0.34
MAOA P21397 1/20 0.34
DRD1 P21728 1/20 0.34
SLC6A2 P23975 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23665555 0.87 DRD4 (0.32) DRD4CYP4F2CYP4A11NPC1RAB9A
SCHEMBL23665530 0.87 DRD4 (0.32) DRD4CYP4F2CYP4A11NPC1RAB9A
SCHEMBL5026596 0.77 CYP1A2 (0.41) KDM4EPOLBMEN1KMT2ACYP1A2
SCHEMBL8540288 0.76 DDB1 (0.36) POLBTP53MEN1KMT2ACYP1A2
SCHEMBL11969974 0.76 POLB (0.36) CYP4F2CYP4A11KDM4EPOLBMEN1
SCHEMBL24337726 0.75 LMNA (0.33) KDM4EPOLBHSD17B10TP53MEN1
SCHEMBL12090322 0.74 CYP4F2 (0.38) DRD4CYP4F2CYP4A11KDM4ENPC1
SCHEMBL12090198 0.74 CYP4F2 (0.39) DRD4CYP4F2CYP4A11KDM4ENPC1
SCHEMBL16125888 0.74 CYP4F2 (0.39) DRD4CYP4F2CYP4A11KDM4ENPC1
SCHEMBL30950223 0.74 CYP4F2 (0.39) DRD4CYP4F2CYP4A11KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220416167-A1 OSMIUM-CONTAINING CONJUGATED POLYMER AND METHODS THEREOF XIAMEN UNIVERSITY (CN) 2022-12-29 US disclosed
WO-2021143690-A1 OSMIUM-CONTAINING CONJUGATED POLYMER, PREPARATION METHOD THEREFOR AND USE THEREOF 厦门大学 2021-07-22 WO disclosed