SCHEMBL8540288

SCHEMBL8540288

Brc1ccc2c3ccccc3n(C3CCCCO3)c2c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DDB1 Q16531 1/20 0.36
CRBN Q96SW2 1/20 0.36
PDE10A Q9Y233 1/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
RAD52 P43351 1/20 0.35
TSPO P30536 1/20 0.34
PER2 O15055 1/20 0.33
CRY1 Q16526 1/20 0.33
CRY2 Q49AN0 1/20 0.33
CDK4 P11802 2/20 0.33
CDK2 P24941 2/20 0.33
MAPT P10636 2/20 0.33
CHEK1 O14757 1/20 0.33
CCNE2 O96020 1/20 0.33
CDK1 P06493 1/20 0.33
CCND1 P24385 1/20 0.33
CCNE1 P24864 1/20 0.33
MAP3K5 Q99683 1/20 0.32
NPSR1 Q6W5P4 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5026596 0.87 CYP1A2 (0.41) DDB1CRBNPDE10AMEN1KMT2A
SCHEMBL2327258 0.84 MAPT (0.46) MEN1KMT2ARAD52TSPOMAPT
SCHEMBL11969974 0.84 POLB (0.36) PDE10AMEN1KMT2APER2CRY1
SCHEMBL11969965 0.79 DHFR (0.39) PDE10AMEN1KMT2ACDK4CDK2
SCHEMBL28019901 0.79 ALDH1A1 (0.43) DDB1CRBNMEN1KMT2ARAD52
SCHEMBL31658978 0.78 CYP4F2 (0.36) DDB1CRBNPDE10AMEN1KMT2A
SCHEMBL31658983 0.77 KDM4E (0.37) MEN1KMT2APER2CRY1CRY2
SCHEMBL30951237 0.77 KDM4E (0.37) MEN1KMT2APER2CRY1CRY2
SCHEMBL14058572 0.76 CHRM1 (0.36) PDE10AMEN1KMT2AALDH1A1MAPK1
SCHEMBL23665463 0.76 DRD4 (0.37) MEN1KMT2AMAPTNPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11591356-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-02-28 US disclosed
US-20220119434-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-04-21 US disclosed
US-20220119434-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2022-04-21 US disclosed
US-11121328-B2 Synthesis of platinum and palladium complexes as narrow-band phosphorescent emitters for full color displays ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2021-09-14 US disclosed
US-11121328-B2 Synthesis of platinum and palladium complexes as narrow-band phosphorescent emitters for full color displays ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2021-09-14 US disclosed
US-10975113-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-04-13 US disclosed
US-10975113-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2021-04-13 US disclosed
US-20200403167-A1 Synthesis of Platinum and Palladium Complexes as Narrow-Band Phosphorescent Emitters for Full Color Displays NATIONAL SCIENCE FOUNDATION 2020-12-24 US disclosed
US-20200403167-A1 Synthesis of Platinum and Palladium Complexes as Narrow-Band Phosphorescent Emitters for Full Color Displays NATIONAL SCIENCE FOUNDATION 2020-12-24 US disclosed
US-10804476-B2 Synthesis of platinum and palladium complexes as narrow-band phosphorescent emitters for full color displays ARIZONA BOARD OF REGENTS, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2020-10-13 US disclosed
US-20160197291-A1 Synthesis of Platinum and Palladium Complexes as Narrow-Band Phosphorescent Emitters for Full Color Displays NATIONAL SCIENCE FOUNDATION 2016-07-07 US disclosed
US-9238668-B2 Synthesis of platinum and palladium complexes as narrow-band phosphorescent emitters for full color displays ARIZONA BOARD OF REGENTS, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2016-01-19 US disclosed
US-9238668-B2 Synthesis of platinum and palladium complexes as narrow-band phosphorescent emitters for full color displays ARIZONA BOARD OF REGENTS, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2016-01-19 US disclosed
US-9238668-B2 Synthesis of platinum and palladium complexes as narrow-band phosphorescent emitters for full color displays ARIZONA BOARD OF REGENTS, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2016-01-19 US disclosed
WO-2012162488-A1 SYNTHESIS OF PLATINUM AND PALLADIUM COMPLEXES AS NARROW-BAND PHOSPHORESCENT EMITTERS FOR FULL COLOR DISPLAYS ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2012-11-29 WO disclosed
US-20120302753-A1 SYNTHESIS OF PLATINUM AND PALLADIUM COMPLEXES AS NARROW-BAND PHOSPHORESCENT EMITTERS FOR FULL COLOR DISPLAYS NATIONAL SCIENCE FOUNDATION 2012-11-29 US disclosed
US-20120302753-A1 SYNTHESIS OF PLATINUM AND PALLADIUM COMPLEXES AS NARROW-BAND PHOSPHORESCENT EMITTERS FOR FULL COLOR DISPLAYS NATIONAL SCIENCE FOUNDATION 2012-11-29 US disclosed
WO-2012162488-A1 SYNTHESIS OF PLATINUM AND PALLADIUM COMPLEXES AS NARROW-BAND PHOSPHORESCENT EMITTERS FOR FULL COLOR DISPLAYS ARIZONA BOARD OF REGENTS ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2012-11-29 WO disclosed
US-20120302753-A1 SYNTHESIS OF PLATINUM AND PALLADIUM COMPLEXES AS NARROW-BAND PHOSPHORESCENT EMITTERS FOR FULL COLOR DISPLAYS NATIONAL SCIENCE FOUNDATION 2012-11-29 US disclosed
EP-0820989-A1 IMIDAZOLE DERIVATIVES AND MEDICINAL COMPOSITION THEREOF YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) 1998-01-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160197291-A1 Synthesis of Platinum and Palladium Complexes as Narrow-Band Phosphorescent Emitters for Full Color Displays DPYD, PAICS, PDCD11 DDB1 75/4885CRBN 1715/4885PDE10A 2368/4885
US-11121328-B2 Synthesis of platinum and palladium complexes as narrow-band phosphorescent emitters for full color displays DPYD, PAICS, PDCD11 DDB1 75/4885CRBN 1715/4885PDE10A 2368/4885
US-11591356-B2 Organic electroluminescent materials and devices L1CAM, SOD1, EPCAM DDB1 1847/4885CRBN 2835/4885PDE10A 4346/4885
US-20220119434-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, SOD1, EPCAM DDB1 1525/4885CRBN 3558/4885PDE10A 4159/4885
US-20200403167-A1 Synthesis of Platinum and Palladium Complexes as Narrow-Band Phosphorescent Emitters for Full Color Displays DPYD, PAICS, PDCD11 DDB1 75/4885CRBN 1715/4885PDE10A 2368/4885
US-10975113-B2 Organic electroluminescent materials and devices OSBPL3, OCIAD1, OSBP DDB1 2859/4885CRBN 4870/4885PDE10A 4258/4885
US-10804476-B2 Synthesis of platinum and palladium complexes as narrow-band phosphorescent emitters for full color displays DPYD, PAICS, PDCD11 DDB1 75/4885CRBN 1715/4885PDE10A 2368/4885
US-20120302753-A1 SYNTHESIS OF PLATINUM AND PALLADIUM COMPLEXES AS NARROW-BAND PHOSPHORESCENT EMITTERS FOR FULL COLOR DISPLAYS DPYD, PAICS, PDCD11 DDB1 60/4885CRBN 1690/4885PDE10A 2447/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.