Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.47 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 3/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | CTSS | P25774 | 2/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27683505 | 1.00 | KLK5 (0.48) | KLK5SCN9ACYP3A4NLRP3REN | |
| SCHEMBL13323781 | 1.00 | KLK5 (0.48) | KLK5SCN9ACYP3A4NLRP3REN | |
| SCHEMBL13323784 | 0.91 | ACE (0.52) | SCN9ACYP3A4RENCTSLCTSB | |
| SCHEMBL2367464 | 0.91 | ACE (0.52) | SCN9ACYP3A4RENCTSLCTSB | |
| SCHEMBL12290542 | 0.91 | KLK5 (0.55) | KLK5SCN9ACYP3A4NLRP3REN | |
| SCHEMBL21875889 | 0.91 | KLK5 (0.55) | KLK5SCN9ACYP3A4NLRP3REN | |
| SCHEMBL2367394 | 0.91 | KLK5 (0.55) | KLK5SCN9ACYP3A4NLRP3REN | |
| SCHEMBL30547271 | 0.91 | KLK5 (0.55) | KLK5SCN9ACYP3A4NLRP3REN | |
| SCHEMBL3820580 | 0.89 | KLK5 (0.48) | KLK5SCN9ACYP3A4NLRP3REN | |
| SCHEMBL16313963 | 0.85 | SCN9A (0.46) | KLK5SCN9ACYP3A4NLRP3REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007794-B1 | LYSOBACTIN AMIDES | AICURIS GMBH & CO KG (DE) | 2011-09-14 | — | — | EP | disclosed |
| CN-101466729-A | Lysobactin amides | AICURIS GMBH & CO KG (DE) | 2009-06-24 | — | — | CN | disclosed |
| EP-2007794-A1 | LYSOBACTIN AMIDES | AiCuris GmbH & Co. KG (DE) | 2008-12-31 | — | — | EP | disclosed |
| US-20080070884-A1 | Antibiotics; novel class of cell wall biosynthesis inhibitors without cross-resistances to known classes of antibiotics; active analogs of lysobactin with a higher ring stability | AICURIS GMBH & CO. KG (DE) | 2008-03-20 | — | — | US | disclosed |
| WO-2007118691-A1 | LYSOBACTIN AMIDES | AICURIS GMBH & CO. KG (DE) | 2007-10-25 | — | — | WO | disclosed |
| CN-101056887-A | Acylated nonadepsipeptides used as lysobactin derivatives | AICURIS GMBH & CO KG (DE) | 2007-10-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070884-A1 | Antibiotics; novel class of cell wall biosynthesis inhibitors without cross-resistances to known classes of antibiotics; active analogs of lysobactin with a higher ring stability | AAAS, PGLS, NRDC | KLK5 2925/4885SCN9A 4101/4885CYP3A4 4034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.