Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | ACE | P12821 | 1/20 | 0.49 |
| ▸ | MDM4 | O15151 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.45 |
| ▸ | ITGAV | P06756 | 3/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | SLC17A5 | Q9NRA2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31369581 | 0.91 | MDM2 (0.57) | MDM2EPHX2ACEMDM4TP53 | |
| SCHEMBL31369804 | 0.91 | MDM2 (0.58) | MDM2EPHX2MDM4TP53CTSS | |
| SCHEMBL3728072 | 0.90 | MDM2 (0.62) | MDM2EPHX2ACEMDM4TP53 | |
| SCHEMBL14039181 | 0.90 | MDM2 (0.62) | MDM2EPHX2ACEMDM4TP53 | |
| SCHEMBL29445607 | 0.90 | MDM2 (0.62) | MDM2EPHX2ACEMDM4TP53 | |
| SCHEMBL29401511 | 0.90 | MDM2 (0.62) | MDM2EPHX2ACEMDM4TP53 | |
| SCHEMBL2307978 | 0.90 | MDM2 (0.62) | MDM2EPHX2ACEMDM4TP53 | |
| SCHEMBL30340155 | 0.89 | MDM2 (0.48) | MDM2EPHX2ACEMDM4TP53 | |
| SCHEMBL23042774 | 0.87 | ACE (0.49) | MDM2ACEMDM4TP53CTSB | |
| SCHEMBL29687511 | 0.87 | ACE (0.49) | MDM2ACEMDM4TP53CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007794-B1 | LYSOBACTIN AMIDES | AICURIS GMBH & CO KG (DE) | 2011-09-14 | — | — | EP | disclosed |