Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.57 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.54 |
| ▸ | ITGAV | P06756 | 7/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | CTSS | P25774 | 1/20 | 0.46 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | MDM4 | O15151 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31370376 | 0.93 | MDM2 (0.64) | MDM2ITGB3ITGAVPTPN1ACE | |
| SCHEMBL2367217 | 0.91 | MDM2 (0.56) | MDM2ITGB3ITGAVPTPN1EPHX2 | |
| SCHEMBL2307978 | 0.90 | MDM2 (0.62) | MDM2ITGB3ITGAVPTPN1EPHX2 | |
| SCHEMBL29445607 | 0.90 | MDM2 (0.62) | MDM2ITGB3ITGAVPTPN1EPHX2 | |
| SCHEMBL3728072 | 0.90 | MDM2 (0.62) | MDM2ITGB3ITGAVPTPN1EPHX2 | |
| SCHEMBL29401511 | 0.90 | MDM2 (0.62) | MDM2ITGB3ITGAVPTPN1EPHX2 | |
| SCHEMBL14039181 | 0.90 | MDM2 (0.62) | MDM2ITGB3ITGAVPTPN1EPHX2 | |
| SCHEMBL24899412 | 0.87 | MDM2 (0.48) | MDM2ITGB3ITGAVPTPN1ACE | |
| SCHEMBL24899413 | 0.87 | MDM2 (0.48) | MDM2ITGB3ITGAVPTPN1ACE | |
| SCHEMBL30421759 | 0.87 | MDM2 (0.48) | MDM2ITGB3ITGAVPTPN1ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2024-12-05 | — | — | US | claimed |
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2024-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | BCAT1, BCAT2, PELP1 | MDM2 2036/4885ITGB3 4142/4885ITGAV 2622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.