SCHEMBL2372530

CC(C)C[C@H](NC(=O)[C@@H](N)[C@H](O)C(C)C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](C[Si](C)(C)C)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](COC(=O)C(F)(F)F)C(=O)N[C@@H](COC(=O)C(F)(F)F)C(=O)O)[C@H](C)O

nearest known ligand 0.40

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	NPY4R	P50391	8/20	0.40

▸	KEAP1	Q14145	2/20	0.38

▸	NPY1R	P25929	4/20	0.36

▸	RAMP3	O60896	4/20	0.36

▸	CALCR	P30988	4/20	0.36

▸	OPRM1	P35372	2/20	0.35

▸	OPRD1	P41143	2/20	0.35

▸	OPRK1	P41145	2/20	0.35

▸	NPY2R	P49146	3/20	0.35

▸	NPY5R	Q15761	3/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL2367191	0.95	NPY4R (0.43)	NPY4RKEAP1NPY1ROPRM1OPRD1
SCHEMBL2367313	0.94	NPY4R (0.42)	NPY4RKEAP1NPY1RRAMP3CALCR
SCHEMBL2367458	0.92	RXFP1 (0.35)	NPY4RKEAP1
SCHEMBL2367091	0.91	RXFP1 (0.41)	NPY4RKEAP1NPY1RNPY2RNPY5R
SCHEMBL2373308	0.89	NPY4R (0.50)	NPY4RKEAP1NPY1ROPRM1OPRD1
SCHEMBL2368042	0.88	RXFP1 (0.44)	NPY4RKEAP1NPY1RNPY2RNPY5R
SCHEMBL2367128	0.88	NPY4R (0.41)	NPY4RKEAP1NPY1RRAMP3CALCR
SCHEMBL2366814	0.88	RXFP1 (0.42)	NPY4RKEAP1NPY1RNPY2RNPY5R
SCHEMBL2367832	0.88	RXFP1 (0.37)	NPY4RKEAP1
SCHEMBL13723352	0.87	OPRM1 (0.44)	NPY4RKEAP1NPY1RRAMP3CALCR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2007794-B1	LYSOBACTIN AMIDES	AICURIS GMBH & CO KG (DE)	2011-09-14	—	—	EP	disclosed