Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 3/20 | 0.37 |
| ▸ | PLAU | P00749 | 2/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.30 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2366962 | 1.00 | PLG (0.37) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL29469785 | 0.85 | MDM2 (0.42) | PLGPLAUF10KLKB1 | |
| SCHEMBL2366956 | 0.85 | MDM2 (0.42) | PLGPLAUF10KLKB1 | |
| SCHEMBL2367323 | 0.85 | MDM2 (0.42) | PLGPLAUF10KLKB1 | |
| SCHEMBL9233971 | 0.85 | PLG (0.44) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL4094903 | 0.85 | PLG (0.37) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL29823593 | 0.85 | HDAC3 (0.36) | PLGPLAUF10KLKB1F2 | |
| SCHEMBL14374808 | 0.84 | PLG (0.36) | PLGPLAUF10KLKB1KMT2A | |
| SCHEMBL4430880 | 0.84 | CASP3 (0.39) | PLGPLAUF10KLKB1KMT2A | |
| SCHEMBL8597568 | 0.83 | PLG (0.35) | PLGPLAUF10KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007794-B1 | LYSOBACTIN AMIDES | AICURIS GMBH & CO KG (DE) | 2011-09-14 | — | — | EP | disclosed |