Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 6/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.38 |
| ▸ | PLG | P00747 | 2/20 | 0.37 |
| ▸ | MDM4 | O15151 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29469785 | 1.00 | MDM2 (0.42) | MDM2TLR2PLGMDM4TP53 | |
| SCHEMBL2366956 | 1.00 | MDM2 (0.42) | MDM2TLR2PLGMDM4TP53 | |
| SCHEMBL14374808 | 0.94 | PLG (0.36) | MDM2TLR2PLGF10PLAU | |
| SCHEMBL29430340 | 0.93 | MDM2 (0.43) | MDM2TLR2MDM4TP53CASP3 | |
| SCHEMBL3431396 | 0.93 | MDM2 (0.43) | MDM2TLR2MDM4TP53CASP3 | |
| SCHEMBL29384293 | 0.93 | MDM2 (0.43) | MDM2TLR2MDM4TP53CASP3 | |
| SCHEMBL29358841 | 0.93 | MDM2 (0.43) | MDM2TLR2MDM4TP53CASP3 | |
| SCHEMBL3725103 | 0.93 | MDM2 (0.43) | MDM2TLR2MDM4TP53CASP3 | |
| SCHEMBL15521023 | 0.93 | MDM2 (0.43) | MDM2TLR2MDM4TP53CASP3 | |
| SCHEMBL31758244 | 0.91 | MDM2 (0.42) | MDM2TLR2MDM4TP53CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8076285-B2 | Lysobactin amides | AICURIS GMBH & CO. KG (DE) | 2011-12-13 | — | — | US | disclosed |
| EP-2007794-B1 | LYSOBACTIN AMIDES | AICURIS GMBH & CO KG (DE) | 2011-09-14 | — | — | EP | disclosed |
| US-20090203582-A1 | LYSOBACTIN AMIDES | BAYER HEALTHCARE AG (DE) | 2009-08-13 | — | — | US | disclosed |
| US-7332301-B2 | Insulin-like growth factor binding protein | KYOWA HAAKKO KOGYO CO. LTD. (JP) | 2008-02-19 | — | — | US | disclosed |
| US-20060216739-A1 | Insulin-like growth factor binding protein | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-09-28 | — | — | US | disclosed |
| US-7071160-B2 | Insulin-like growth factor-binding protein | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2006-07-04 | — | — | US | disclosed |
| US-20040072238-A1 | Insulin-like growth factor-binding protein | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2004-04-15 | — | — | US | disclosed |
| EP-1295939-A1 | INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2003-03-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203582-A1 | LYSOBACTIN AMIDES | AADAT, HAMP, DLST | MDM2 4472/4885TLR2 23/4885PLG 658/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.