Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | BRD4 | O60885 | 2/20 | 0.42 |
| ▸ | BRD2 | P25440 | 1/20 | 0.42 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.42 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.42 |
| ▸ | DUT | P33316 | 1/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23113070 | 0.75 | NOTUM (0.46) | ALDH1A1BRD4BRD2BRD3BRDT | |
| SCHEMBL25119665 | 0.74 | HDAC8 (0.45) | ALDH1A1BRD4BRD2BRD3BRDT | |
| SCHEMBL22535064 | 0.74 | HDAC8 (0.41) | ALDH1A1BRD4BRD2BRD3BRDT | |
| SCHEMBL8528623 | 0.73 | MAPT (0.43) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL23113030 | 0.72 | CA12 (0.49) | ALDH1A1DUTMEN1KMT2AKDM4E | |
| SCHEMBL23113075 | 0.71 | CRHBP (0.49) | ALDH1A1BRD4BRD2BRD3BRDT | |
| SCHEMBL13492176 | 0.67 | HDAC8 (0.47) | ALDH1A1BRD4BRD2BRD3BRDT | |
| SCHEMBL349527 | 0.66 | MAPT (0.66) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL2803354 | 0.65 | NSD2 (0.58) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL634086 | 0.65 | CA1 (0.57) | ALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11459296-B2 | Antibacterial compounds | Infex Therapeutics Limited (GB) | 2022-10-04 | — | — | US | disclosed |
| US-20210230115-A1 | Antibacterial Compounds | Infex Therapeutics Limited (GB) | 2021-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210230115-A1 | Antibacterial Compounds | GAA, MGAM, NQO1 | ALDH1A1 291/4885BRD4 2163/4885BRD2 4105/4885 |
| US-11459296-B2 | Antibacterial compounds | GAA, MGAM, NQO1 | ALDH1A1 291/4885BRD4 2163/4885BRD2 4105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.