Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 2/20 | 0.40 |
| ▸ | PARG | Q86W56 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.34 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8319074 | 0.75 | KDM4E (0.45) | MAPTSMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL23673265 | 0.73 | ALDH1A1 (0.43) | MAPTSMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL14030743 | 0.71 | TSHR (0.46) | MAPTSMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL4321935 | 0.70 | TSHR (0.50) | MAPTSMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL7595602 | 0.70 | TSHR (0.45) | MAPTSMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL4321937 | 0.70 | CA2 (0.45) | MAPTSMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL8528220 | 0.69 | NSD2 (0.39) | MAPTSMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL2803354 | 0.69 | NSD2 (0.58) | MAPTSMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL22535063 | 0.67 | TSHR (0.38) | MAPTMEN1KMT2AALDH1A1TSHR | |
| SCHEMBL19913357 | 0.67 | TSHR (0.42) | MAPTSMN1; SMN2MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723410-A | PLANT GROWTH REGULATORS AND HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-03-03 | — | — | US | disclosed |
| EP-0546082-B1 | HERBICIDAL PYRROLESULFONYLUREAS | DU PONT (US) | 1996-12-18 | — | — | EP | disclosed |
| US-5585328-A | PLANT GROWTH REGULATORS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-12-17 | — | — | US | disclosed |
| US-5472933-A | Plant growth regulators | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-12-05 | — | — | US | disclosed |
| EP-0546082-A1 | HERBICIDAL PYRROLESULFONYLUREAS. | DU PONT (US) | 1993-06-16 | — | — | EP | disclosed |
| WO-1992004319-A1 | HERBICIDAL PYRROLESULFONYLUREAS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-03-19 | — | — | WO | disclosed |