Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | VDR | P11473 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4409966 | 0.85 | CYP1A1 (0.49) | SMN1; SMN2TP53MAPTCYP1A2CYP3A4 | |
| SCHEMBL1130768 | 0.85 | CLK4 (0.56) | CLK4DYRK1ACYP19A1NR1H2NR1H3 | |
| SCHEMBL644691 | 0.82 | CLK4 (0.47) | CLK4SMN1; SMN2TP53MAPTNPC1 | |
| SCHEMBL4415773 | 0.79 | PDGFRB (0.43) | SMN1; SMN2TP53MAPTNPC1RAB9A | |
| SCHEMBL5574497 | 0.79 | CYP19A1 (0.42) | CYP19A1SMN1; SMN2TP53MAPTNPC1 | |
| SCHEMBL2367747 | 0.76 | NPC1 (0.38) | NR1H2NR1H3SMN1; SMN2TP53MAPT | |
| SCHEMBL4413811 | 0.76 | KDM4E (0.39) | CYP19A1SMN1; SMN2TP53MAPTCYP1A2 | |
| SCHEMBL27559198 | 0.75 | CLK4 (0.73) | CLK4DYRK1ACYP19A1NR1H2NR1H3 | |
| SCHEMBL27689580 | 0.73 | NPC1 (0.39) | SMN1; SMN2MAPTCYP1A2NPC1RAB9A | |
| SCHEMBL4901265 | 0.73 | VDR (0.54) | CLK4DYRK1ACYP19A1NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2375287-B1 | Radiation sensitive composition | FOUNDER FINE CHEMICAL INDUSTRY CO LTD (TW) | 2013-06-05 | — | — | EP | disclosed |
| EP-2366544-B1 | Radiation sensitive composition | FOUNDER FINE CHEMICAL INDUSTRY CO LTD (TW) | 2012-07-18 | — | — | EP | disclosed |
| EP-2375287-A1 | Radiation sensitive composition | Founder Fine Chemical Industry Co., Ltd. (TW) | 2011-10-12 | — | — | EP | disclosed |
| EP-2366544-A1 | Radiation sensitive composition | Founder Fine Chemical Industry Co., Ltd. (TW) | 2011-09-21 | — | — | EP | disclosed |